Crosslinking dynamics and gelation characteristics of photo- and thermally polymerized poly(ethylene glycol) hydrogels

Jungmoon Sung; Dong Geun Lee; Sukchin Lee; Junyoung Park; Hyun Wook Jung

doi:10.3390/MA13153277

Crosslinking dynamics and gelation characteristics of photo- and thermally polymerized poly(ethylene glycol) hydrogels

Jungmoon Sung, Dong Geun Lee, Sukchin Lee, Junyoung Park, Hyun Wook Jung

Department of Chemical and Biological Engineering

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

The crosslinking behaviors and gelation features of poly(ethylene glycol) (PEG) hydrogels were scrutinized during the UV and thermal polymerizations of mixtures of poly(ethylene glycol) methacrylate (PEGMA, monomer) and poly(ethylene glycol) dimethacrylates (PEGDMAs, crosslinkers). The real-time crosslinking behavior of the PEG hydrogels was quantified as a function of the UV irradiation time and reaction temperature during the UV and thermal polymerization, respectively, using real-time FT-IR spectrometry and rotational rheometry. The gelation characteristics of UV- and thermally crosslinked hydrogels were compared through the analysis of the gel fraction, swelling ratio, surface hardness, and the loading and release of rhodamine-B. The gelation properties of the cured hydrogel films were suitably correlated with the real-time rheological properties and crosslinked network state of the PEG mixtures. The crosslinking and gelation properties of the cured hydrogels could be optimally tuned by not only the molecular weight of the crosslinker but also the UV or thermal polymerization conditions.

Original language	English
Article number	3277
Journal	Materials
Volume	13
Issue number	15
DOIs	https://doi.org/10.3390/MA13153277
Publication status	Published - 2020

Keywords

Gelation properties
PEG hydrogel
Real-time FT-IR
Rheological properties
UV and thermal crosslinking

ASJC Scopus subject areas

Materials Science(all)
Condensed Matter Physics

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title = "Crosslinking dynamics and gelation characteristics of photo- and thermally polymerized poly(ethylene glycol) hydrogels",

abstract = "The crosslinking behaviors and gelation features of poly(ethylene glycol) (PEG) hydrogels were scrutinized during the UV and thermal polymerizations of mixtures of poly(ethylene glycol) methacrylate (PEGMA, monomer) and poly(ethylene glycol) dimethacrylates (PEGDMAs, crosslinkers). The real-time crosslinking behavior of the PEG hydrogels was quantified as a function of the UV irradiation time and reaction temperature during the UV and thermal polymerization, respectively, using real-time FT-IR spectrometry and rotational rheometry. The gelation characteristics of UV- and thermally crosslinked hydrogels were compared through the analysis of the gel fraction, swelling ratio, surface hardness, and the loading and release of rhodamine-B. The gelation properties of the cured hydrogel films were suitably correlated with the real-time rheological properties and crosslinked network state of the PEG mixtures. The crosslinking and gelation properties of the cured hydrogels could be optimally tuned by not only the molecular weight of the crosslinker but also the UV or thermal polymerization conditions.",

keywords = "Gelation properties, PEG hydrogel, Real-time FT-IR, Rheological properties, UV and thermal crosslinking",

author = "Jungmoon Sung and Lee, {Dong Geun} and Sukchin Lee and Junyoung Park and Jung, {Hyun Wook}",

note = "Funding Information: Funding: This research was funded by the Ministry of Trade, Industry & Energy (MOTIE, Korea) under the Industrial Technology Innovation Program (no. 10067082 and no. 20004044). Publisher Copyright: {\textcopyright} 2020 by the authors.",

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doi = "10.3390/MA13153277",

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AU - Lee, Dong Geun

AU - Lee, Sukchin

AU - Park, Junyoung

AU - Jung, Hyun Wook

N1 - Funding Information: Funding: This research was funded by the Ministry of Trade, Industry & Energy (MOTIE, Korea) under the Industrial Technology Innovation Program (no. 10067082 and no. 20004044). Publisher Copyright: © 2020 by the authors.

PY - 2020

Y1 - 2020

N2 - The crosslinking behaviors and gelation features of poly(ethylene glycol) (PEG) hydrogels were scrutinized during the UV and thermal polymerizations of mixtures of poly(ethylene glycol) methacrylate (PEGMA, monomer) and poly(ethylene glycol) dimethacrylates (PEGDMAs, crosslinkers). The real-time crosslinking behavior of the PEG hydrogels was quantified as a function of the UV irradiation time and reaction temperature during the UV and thermal polymerization, respectively, using real-time FT-IR spectrometry and rotational rheometry. The gelation characteristics of UV- and thermally crosslinked hydrogels were compared through the analysis of the gel fraction, swelling ratio, surface hardness, and the loading and release of rhodamine-B. The gelation properties of the cured hydrogel films were suitably correlated with the real-time rheological properties and crosslinked network state of the PEG mixtures. The crosslinking and gelation properties of the cured hydrogels could be optimally tuned by not only the molecular weight of the crosslinker but also the UV or thermal polymerization conditions.

AB - The crosslinking behaviors and gelation features of poly(ethylene glycol) (PEG) hydrogels were scrutinized during the UV and thermal polymerizations of mixtures of poly(ethylene glycol) methacrylate (PEGMA, monomer) and poly(ethylene glycol) dimethacrylates (PEGDMAs, crosslinkers). The real-time crosslinking behavior of the PEG hydrogels was quantified as a function of the UV irradiation time and reaction temperature during the UV and thermal polymerization, respectively, using real-time FT-IR spectrometry and rotational rheometry. The gelation characteristics of UV- and thermally crosslinked hydrogels were compared through the analysis of the gel fraction, swelling ratio, surface hardness, and the loading and release of rhodamine-B. The gelation properties of the cured hydrogel films were suitably correlated with the real-time rheological properties and crosslinked network state of the PEG mixtures. The crosslinking and gelation properties of the cured hydrogels could be optimally tuned by not only the molecular weight of the crosslinker but also the UV or thermal polymerization conditions.

KW - Gelation properties

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KW - Real-time FT-IR

KW - Rheological properties

KW - UV and thermal crosslinking

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Crosslinking dynamics and gelation characteristics of photo- and thermally polymerized poly(ethylene glycol) hydrogels

Abstract

Keywords

ASJC Scopus subject areas

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