TY - JOUR
T1 - Decreased peripheral and central responses to acupuncture stimulation following modification of body ownership e109489
AU - Chae, Younbyoung
AU - Lee, In Seon
AU - Jung, Won Mo
AU - Chang, Dong Seon
AU - Napadow, Vitaly
AU - Lee, Hyejung
AU - Park, Hi Joon
AU - Wallraven, Christian
N1 - Publisher Copyright:
© 2014 Chae et al.
Copyright:
Copyright 2014 Elsevier B.V., All rights reserved.
PY - 2014/10/6
Y1 - 2014/10/6
N2 - Acupuncture stimulation increases local blood flow around the site of stimulation and induces signal changes in brain regions related to the body matrix. The rubber hand illusion (RHI) is an experimental paradigm that manipulates important aspects of bodily self-awareness. The present study aimed to investigate how modifications of body ownership using the RHI affect local blood flow and cerebral responses during acupuncture needle stimulation. During the RHI, acupuncture needle stimulation was applied to the real left hand while measuring blood microcirculation with a LASER Doppler imager (Experiment 1, A/ = 28) and concurrent brain signal changes using functional magnetic resonance imaging (fMRI; Experiment 2, Af = 17). When the body ownership of participants was altered by the RHI, acupuncture stimulation resulted in a significantly lower increase in local blood flow (Experiment 1), and significantly less brain activation was detected in the right insula (Experiment 2). This study found changes in both local blood flow and brain responses during acupuncture needle stimulation following modification of body ownership. These findings suggest that physiological responses during acupuncture stimulation can be influenced by the modification of body ownership.
AB - Acupuncture stimulation increases local blood flow around the site of stimulation and induces signal changes in brain regions related to the body matrix. The rubber hand illusion (RHI) is an experimental paradigm that manipulates important aspects of bodily self-awareness. The present study aimed to investigate how modifications of body ownership using the RHI affect local blood flow and cerebral responses during acupuncture needle stimulation. During the RHI, acupuncture needle stimulation was applied to the real left hand while measuring blood microcirculation with a LASER Doppler imager (Experiment 1, A/ = 28) and concurrent brain signal changes using functional magnetic resonance imaging (fMRI; Experiment 2, Af = 17). When the body ownership of participants was altered by the RHI, acupuncture stimulation resulted in a significantly lower increase in local blood flow (Experiment 1), and significantly less brain activation was detected in the right insula (Experiment 2). This study found changes in both local blood flow and brain responses during acupuncture needle stimulation following modification of body ownership. These findings suggest that physiological responses during acupuncture stimulation can be influenced by the modification of body ownership.
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U2 - 10.1371/journal.pone.0109489
DO - 10.1371/journal.pone.0109489
M3 - Article
C2 - 25285620
AN - SCOPUS:84907828147
VL - 9
JO - PLoS One
JF - PLoS One
SN - 1932-6203
IS - 10
M1 - e109489
ER -