Decreased serum epinephrine in children with positive skin prick test

Seok Chan Hong, Jeffrey D. Suh, Sochung Chung, Seung Hoon Lee, Ji Ho Choi, Jeong In Oh, In Tae Kim, Jin Kook Kim, Jae Hoon Cho

Research output: Contribution to journalArticle

Abstract

Objectives. To evaluate the association between catecholamine levels and skin prick test results among children. Methods. Two hundred eight first grade children from one elementary school were invited to participate in this study. Skin prick test (SPT) for six allergens (2 house dust mites, cat, dog, mugwort, and pollen mixture) was performed, and patient demographic information was recorded. The parents were surveyed using questionnaires about rhinitis-related symptoms. Finally, venous blood sampling was done to measure catecholamine levels (epinephrine, norepinephrine, and dopamine) by high-performance liquid chromatography. Results. Out of 208 children, 174 (106 boys and 68 girls) enrolled in this study. Ninety-six of the children (55%) had negative SPT (nonsensitization group), while 78 (45%) had a positive SPT to at least one of six allergens (sensitization group). The diagnosis of chronic rhinitis was more prevalent in the sensitization group (35.9%) than nonsensitization group (26.0%), however the finding was not significant (P=0.186). Epinephrine levels were decreased between the sensitization group compared to the nonsensitization group (P=0.004). There was no difference in norepinephrine and dopamine levels (P>0.05). Conclusion. Epinephrine levels are lower in children with positive SPT compared to controls, however, the level of the catecholamine was not associated with the presence or absence of rhinitis symptoms.

Original languageEnglish
Pages (from-to)381-384
Number of pages4
JournalClinical and Experimental Otorhinolaryngology
Volume8
Issue number4
DOIs
Publication statusPublished - 2015 Jan 1

Fingerprint

Skin Tests
Epinephrine
Rhinitis
Catecholamines
Serum
Dopamine
Norepinephrine
Dermatophagoides Antigens
Artemisia
Pollen
Allergens
Cats
Parents
High Pressure Liquid Chromatography
Demography
Dogs

Keywords

  • Allergic rhinitis
  • Child
  • Epinephrine
  • Skin tests

ASJC Scopus subject areas

  • Surgery
  • Otorhinolaryngology

Cite this

Decreased serum epinephrine in children with positive skin prick test. / Hong, Seok Chan; Suh, Jeffrey D.; Chung, Sochung; Lee, Seung Hoon; Choi, Ji Ho; Oh, Jeong In; Kim, In Tae; Kim, Jin Kook; Cho, Jae Hoon.

In: Clinical and Experimental Otorhinolaryngology, Vol. 8, No. 4, 01.01.2015, p. 381-384.

Research output: Contribution to journalArticle

Hong, SC, Suh, JD, Chung, S, Lee, SH, Choi, JH, Oh, JI, Kim, IT, Kim, JK & Cho, JH 2015, 'Decreased serum epinephrine in children with positive skin prick test', Clinical and Experimental Otorhinolaryngology, vol. 8, no. 4, pp. 381-384. https://doi.org/10.3342/ceo.2015.8.4.381
Hong, Seok Chan ; Suh, Jeffrey D. ; Chung, Sochung ; Lee, Seung Hoon ; Choi, Ji Ho ; Oh, Jeong In ; Kim, In Tae ; Kim, Jin Kook ; Cho, Jae Hoon. / Decreased serum epinephrine in children with positive skin prick test. In: Clinical and Experimental Otorhinolaryngology. 2015 ; Vol. 8, No. 4. pp. 381-384.
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