Decursinol angelate

A cytotoxic and protein kinase C activating agent from the root of Angelica gigas

Kyung Seop Ahn, Woong Seop Sim, In K. Lee, Young B. Seu, Ik Hwan Kim

Research output: Contribution to journalArticle

51 Citations (Scopus)

Abstract

A cytotoxic compound was purified from the root of Angelica gigas Nakai by normal phase HPLC. As a result of the structure analysis by mass, IR, 1H-NMR, and 13C-NMR spectrometry, the compound was identified as decursinol angelate, a structural isomer of decursin, and characterized originally from Sesei grandivittatum. Decursinol angelate showed in vitro cytotoxicity and protein kinase C activating activities like decursin.

Original languageEnglish
Pages (from-to)360-361
Number of pages2
JournalPlanta Medica
Volume63
Issue number4
DOIs
Publication statusPublished - 1997 Aug 14

Fingerprint

Angelica gigas
Angelica
protein kinase C
Protein Kinase C
isomers
cytotoxicity
spectroscopy
Nuclear magnetic resonance
Cytotoxicity
Isomers
Spectrometry
Spectrum Analysis
High Pressure Liquid Chromatography
decursin

ASJC Scopus subject areas

  • Plant Science
  • Organic Chemistry
  • Drug Discovery
  • Pharmacology

Cite this

Decursinol angelate : A cytotoxic and protein kinase C activating agent from the root of Angelica gigas. / Ahn, Kyung Seop; Sim, Woong Seop; Lee, In K.; Seu, Young B.; Kim, Ik Hwan.

In: Planta Medica, Vol. 63, No. 4, 14.08.1997, p. 360-361.

Research output: Contribution to journalArticle

Ahn, Kyung Seop ; Sim, Woong Seop ; Lee, In K. ; Seu, Young B. ; Kim, Ik Hwan. / Decursinol angelate : A cytotoxic and protein kinase C activating agent from the root of Angelica gigas. In: Planta Medica. 1997 ; Vol. 63, No. 4. pp. 360-361.
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