Decursinol angelate: A cytotoxic and protein kinase C activating agent from the root of Angelica gigas

Kyung Seop Ahn, Woong Seop Sim, In K. Lee, Young B. Seu, Ik Hwan Kim

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A cytotoxic compound was purified from the root of Angelica gigas Nakai by normal phase HPLC. As a result of the structure analysis by mass, IR, 1H-NMR, and 13C-NMR spectrometry, the compound was identified as decursinol angelate, a structural isomer of decursin, and characterized originally from Sesei grandivittatum. Decursinol angelate showed in vitro cytotoxicity and protein kinase C activating activities like decursin.

Original languageEnglish
Pages (from-to)360-361
Number of pages2
JournalPlanta Medica
Issue number4
Publication statusPublished - 1997 Aug 14


ASJC Scopus subject areas

  • Plant Science
  • Organic Chemistry
  • Drug Discovery
  • Pharmacology

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