Dedifferentiated liposarcoma of retroperitoneum: Spectrum of imaging findings in 15 patients

Sun Hwa Hong, Kyeong Ah Kim, Ok Hee Woo, Cheol Min Park, Chul Hwan Kim, Myeong Jin Kim, Jae Joon Chung, Joon Koo Han, Sung Eun Rha

Research output: Contribution to journalArticlepeer-review

24 Citations (Scopus)


Background: Dedifferentiated liposarcoma is a high-grade nonlipogenic sarcoma that arises in the background of a preexisting well-differentiated liposarcoma. The purpose of this work is to evaluate the spectrum of radiologic appearance of retroperitoneal dedifferentiated liposarcoma with clinicopathologic features. Methods: Radiologic images and clinical histories of 15 patients with histologically verified retroperitoneal dedifferentiated liposarcoma were retrospectively studied. Patients included 11 men and 4 women, with mean age of 55.8 years (range, 36-74 years), and they underwent computed tomography (CT) (n=15) and magnetic resonance imaging (MRI) (n=5). Results: The mean size of the tumor was 22.6 cm with a range of 9.5-38 cm. Both CT and MRI showed well-circumscribed, large round, or lobulated retroperitoneal mass. The appearance of the tumor was classified as follows: Category I, nonfatty component within predominant fatty mass (n=5); Category II, focal fatty component within large nonfatty mass (n=6); Category III, well-defined fatty mass and well-defined nonfatty mass (n=1); Category IV, two masses with predominantly nonfatty component (n=3). Conclusion: Retroperitoneal dedifferentiated liposarcomas present various spectra of imaging findings. While Categories I and III may suggest dedifferentiated liposarcoma, Categories II and IV may appear as other types of liposarcoma or other malignant retroperitoneal tumor.

Original languageEnglish
Pages (from-to)203-210
Number of pages8
JournalClinical Imaging
Issue number3
Publication statusPublished - 2010 May
Externally publishedYes


  • CT
  • Dedifferentiated
  • Liposarcoma
  • MR
  • Pathology
  • Retroperitoneum

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


Dive into the research topics of 'Dedifferentiated liposarcoma of retroperitoneum: Spectrum of imaging findings in 15 patients'. Together they form a unique fingerprint.

Cite this