Defining CT Perfusion Thresholds for Infarction in the Golden Hour and with Ultra-Early Reperfusion

Mohamed Najm, Fahad S. Al-Ajlan, Mari E. Boesen, Lisa Hur, Chi Kyung Kim, Enrico Fainardi, Michael D. Hill, Andrew M. Demchuk, Mayank Goyal, Ting Y. Lee, Bijoy K. Menon

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6 Citations (Scopus)

Abstract

In this brief report, computed tomography perfusion (CTP) thresholds predicting follow-up infarction in patients presenting <3 hours from stroke onset and achieving ultra-early reperfusion (<45 minutes from CTP) are reported. CTP thresholds that predict follow-up infarction vary based on time to reperfusion: Tmax >20 to 23 seconds and cerebral blood flow <5 to 7 ml/min -1 /(100 g) -1 or relative cerebral blood flow <0.14 to 0.20 optimally predicted the final infarct. These thresholds are stricter than published thresholds.

Original languageEnglish
Pages (from-to)339-342
Number of pages4
JournalCanadian Journal of Neurological Sciences
Volume45
Issue number3
DOIs
Publication statusPublished - 2018 May 1
Externally publishedYes

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Keywords

  • CT perfusion
  • early reperfusion
  • endovascular therapy

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

Cite this

Najm, M., Al-Ajlan, F. S., Boesen, M. E., Hur, L., Kim, C. K., Fainardi, E., Hill, M. D., Demchuk, A. M., Goyal, M., Lee, T. Y., & Menon, B. K. (2018). Defining CT Perfusion Thresholds for Infarction in the Golden Hour and with Ultra-Early Reperfusion. Canadian Journal of Neurological Sciences, 45(3), 339-342. https://doi.org/10.1017/cjn.2017.287