Defining CT Perfusion Thresholds for Infarction in the Golden Hour and with Ultra-Early Reperfusion

Mohamed Najm, Fahad S. Al-Ajlan, Mari E. Boesen, Lisa Hur, Chi Kyung Kim, Enrico Fainardi, Michael D. Hill, Andrew M. Demchuk, Mayank Goyal, Ting Y. Lee, Bijoy K. Menon

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

In this brief report, computed tomography perfusion (CTP) thresholds predicting follow-up infarction in patients presenting <3 hours from stroke onset and achieving ultra-early reperfusion (<45 minutes from CTP) are reported. CTP thresholds that predict follow-up infarction vary based on time to reperfusion: Tmax >20 to 23 seconds and cerebral blood flow <5 to 7 ml/min -1 /(100 g) -1 or relative cerebral blood flow <0.14 to 0.20 optimally predicted the final infarct. These thresholds are stricter than published thresholds.

Original languageEnglish
Pages (from-to)339-342
Number of pages4
JournalCanadian Journal of Neurological Sciences
Volume45
Issue number3
DOIs
Publication statusPublished - 2018 May 1
Externally publishedYes

Fingerprint

Cerebrovascular Circulation
Infarction
Reperfusion
Perfusion
Tomography

Keywords

  • CT perfusion
  • early reperfusion
  • endovascular therapy

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

Cite this

Defining CT Perfusion Thresholds for Infarction in the Golden Hour and with Ultra-Early Reperfusion. / Najm, Mohamed; Al-Ajlan, Fahad S.; Boesen, Mari E.; Hur, Lisa; Kim, Chi Kyung; Fainardi, Enrico; Hill, Michael D.; Demchuk, Andrew M.; Goyal, Mayank; Lee, Ting Y.; Menon, Bijoy K.

In: Canadian Journal of Neurological Sciences, Vol. 45, No. 3, 01.05.2018, p. 339-342.

Research output: Contribution to journalArticle

Najm, M, Al-Ajlan, FS, Boesen, ME, Hur, L, Kim, CK, Fainardi, E, Hill, MD, Demchuk, AM, Goyal, M, Lee, TY & Menon, BK 2018, 'Defining CT Perfusion Thresholds for Infarction in the Golden Hour and with Ultra-Early Reperfusion', Canadian Journal of Neurological Sciences, vol. 45, no. 3, pp. 339-342. https://doi.org/10.1017/cjn.2017.287
Najm, Mohamed ; Al-Ajlan, Fahad S. ; Boesen, Mari E. ; Hur, Lisa ; Kim, Chi Kyung ; Fainardi, Enrico ; Hill, Michael D. ; Demchuk, Andrew M. ; Goyal, Mayank ; Lee, Ting Y. ; Menon, Bijoy K. / Defining CT Perfusion Thresholds for Infarction in the Golden Hour and with Ultra-Early Reperfusion. In: Canadian Journal of Neurological Sciences. 2018 ; Vol. 45, No. 3. pp. 339-342.
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