Deformable registration of tumor-diseased brain images

Tianming Liu, Dinggang Shen, Christos Davatzikos

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Citations (Scopus)

Abstract

This paper presents an approach for deformable registration of a normal brain atlas to visible anatomic structures in a tumor-diseased brain image. We restrict our attention to cortical surfaces. First, a model surface in the atlas is warped to the tumor-diseased brain image via a HAMMER-based volumetric registration algorithm. However, the volumetric warping is generally inaccurate around the tumor region, due to the lack of reliable features to which the atlas can be matched. Therefore, the model structures for which no reliable matches are found are labeled by a Markov Random Field-Maximum A Posteriori approach. A statistically-based interpolation method is then used to correct/refine the volumetric warping for those structures. Finally, with the good initialization obtained by the above steps and the identification of the part of the model anatomy that can be recognized in the patient's image, the model surface is adaptively warped to its counterpart that is visible in the tumor-diseased brain image through a surface registration procedure. Preliminary results show good performance on both simulated and real tumor-diseased brain images.

Original languageEnglish
Title of host publicationLecture Notes in Computer Science
EditorsC. Barillot, D.R. Haynor, P. Hellier
Pages720-728
Number of pages9
Volume3216
EditionPART 1
Publication statusPublished - 2004
Externally publishedYes
EventMedical Image Computing and Computer-Assisted Intervention, MICCAI 2004 - 7th International Conference, Proceedings - Saint-Malo, France
Duration: 2004 Sep 262004 Sep 29

Other

OtherMedical Image Computing and Computer-Assisted Intervention, MICCAI 2004 - 7th International Conference, Proceedings
CountryFrance
CitySaint-Malo
Period04/9/2604/9/29

ASJC Scopus subject areas

  • Computer Science (miscellaneous)

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  • Cite this

    Liu, T., Shen, D., & Davatzikos, C. (2004). Deformable registration of tumor-diseased brain images. In C. Barillot, D. R. Haynor, & P. Hellier (Eds.), Lecture Notes in Computer Science (PART 1 ed., Vol. 3216, pp. 720-728)