Delayed puberty due to pituitary stalk dysgenesis and ectopic neurohypophysis

Hye Jin Yoo; Kyung Mook Choi; Ohk Hyun Ryu; Sang Il Suh; Nan Hee Kim; Sei Hyun Baik; Dong Seop Choi

doi:10.3904/kjim.2006.21.1.68

Delayed puberty due to pituitary stalk dysgenesis and ectopic neurohypophysis

Hye Jin Yoo, Kyung Mook Choi, Ohk Hyun Ryu, Sang Il Suh, Nan Hee Kim, Sei Hyun Baik, Dong Seop Choi

Department of Biomedical Sciences

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

Hypopituitarism is not a common cause of delayed puberty. A 22 year old man was referred to our clinic because of the absence of the development of secondary sexual characteristics. The patient had no complaints of physical discomfort. Random serum testosterone and luteinizing hormone level were obtained and found to be low. The combined pituitary function stimulation test revealed a partial hypopituitarism. A pituitary magnetic resonance imaging (MRI) was obtained and showed decreased pituitary stalk enhancement and ectopic neurohypophysis. Therefore, we conclude that the delayed puberty was a result of hypopituitarism due to pituitary stalk dysgenesis and ectopic neurohypophysis. The patient was started on hormone replacement therapy and gradually developed secondary sexual characteristics.

Original language	English
Pages (from-to)	68-72
Number of pages	5
Journal	Korean Journal of Internal Medicine
Volume	21
Issue number	1
DOIs	https://doi.org/10.3904/kjim.2006.21.1.68
Publication status	Published - 2006 Mar

Keywords

Delayed puberty
Hypopituitarism
Neurohypophysis
Pituitary stalk

ASJC Scopus subject areas

Internal Medicine

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10.3904/kjim.2006.21.1.68

Cite this

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title = "Delayed puberty due to pituitary stalk dysgenesis and ectopic neurohypophysis",

abstract = "Hypopituitarism is not a common cause of delayed puberty. A 22 year old man was referred to our clinic because of the absence of the development of secondary sexual characteristics. The patient had no complaints of physical discomfort. Random serum testosterone and luteinizing hormone level were obtained and found to be low. The combined pituitary function stimulation test revealed a partial hypopituitarism. A pituitary magnetic resonance imaging (MRI) was obtained and showed decreased pituitary stalk enhancement and ectopic neurohypophysis. Therefore, we conclude that the delayed puberty was a result of hypopituitarism due to pituitary stalk dysgenesis and ectopic neurohypophysis. The patient was started on hormone replacement therapy and gradually developed secondary sexual characteristics.",

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AU - Yoo, Hye Jin

AU - Choi, Kyung Mook

AU - Ryu, Ohk Hyun

AU - Suh, Sang Il

AU - Kim, Nan Hee

AU - Baik, Sei Hyun

AU - Choi, Dong Seop

PY - 2006/3

Y1 - 2006/3

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AB - Hypopituitarism is not a common cause of delayed puberty. A 22 year old man was referred to our clinic because of the absence of the development of secondary sexual characteristics. The patient had no complaints of physical discomfort. Random serum testosterone and luteinizing hormone level were obtained and found to be low. The combined pituitary function stimulation test revealed a partial hypopituitarism. A pituitary magnetic resonance imaging (MRI) was obtained and showed decreased pituitary stalk enhancement and ectopic neurohypophysis. Therefore, we conclude that the delayed puberty was a result of hypopituitarism due to pituitary stalk dysgenesis and ectopic neurohypophysis. The patient was started on hormone replacement therapy and gradually developed secondary sexual characteristics.

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KW - Hypopituitarism

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KW - Pituitary stalk

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Delayed puberty due to pituitary stalk dysgenesis and ectopic neurohypophysis

Abstract

Keywords

ASJC Scopus subject areas

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