Depression among HIV-infected patients in Korea: Assessment of clinical significance and risk factors

Joon-Young Song, Jin Soo Lee, Yu Bin Seo, In Seon Kim, Ji Yun Noh, Ji Hyeon Baek, Hee-Jin Cheong, Woo Joo Kim

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Background: With prolonged life expectancies, mental illness has emerged as a disabling disorder among people with HIV. Materials and Methods: This study was conducted to assess the prevalence of depression and its risk factors among Korean patients with HIV infections. Eighty-two HIV-infected patients completed structured questionnaires including the Beck Depression Inventory and the State-Trait Anxiety Inventory. Subjects with depression were compared to those without depression in terms of demographics, comorbidities, CD4 T-cell count, RNA copy numbers, highly active antiretroviral therapy (HAART) regimens, and adherence. Results: The estimated depression rate was 21% (17 of 82 subjects). Comorbidities (47% vs. 20%, P = 0.01) and unemployment (65% vs. 31%, P = 0.02) were risk factors for depression. Depressive patients were more likely to be anxious (71% vs. 29%, P < 0.01), to frequently miss clinical appointments each year (P = 0.04), and to have higher cumulative time lost to follow-up per month (P <0.01) compared to non-depressive patients. Only three depressive patients were referred to neuropsychologists. Conclusions: More than 20% of the Korean HIV patients in this study suffered from depression associated with poor adherence. Considering the low level of recognition of depression by clinicians, risk factor-based active assessment is recommended to manage depression properly in HIV-infected patients.

Original languageEnglish
Pages (from-to)211-216
Number of pages6
JournalInfection and Chemotherapy
Volume45
Issue number2
DOIs
Publication statusPublished - 2013 Sep 23

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Korea
HIV
Depression
Comorbidity
Equipment and Supplies
Unemployment
Lost to Follow-Up
Highly Active Antiretroviral Therapy
CD4 Lymphocyte Count
Life Expectancy
HIV Infections
Appointments and Schedules
Anxiety
Demography
RNA
T-Lymphocytes

Keywords

  • Acquired immunodeficiency syndrome
  • Anxiety
  • Depression
  • HIV

ASJC Scopus subject areas

  • Pharmacology (medical)
  • Infectious Diseases

Cite this

Depression among HIV-infected patients in Korea : Assessment of clinical significance and risk factors. / Song, Joon-Young; Lee, Jin Soo; Seo, Yu Bin; Kim, In Seon; Noh, Ji Yun; Baek, Ji Hyeon; Cheong, Hee-Jin; Kim, Woo Joo.

In: Infection and Chemotherapy, Vol. 45, No. 2, 23.09.2013, p. 211-216.

Research output: Contribution to journalArticle

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