Depressive mood and quality of life in functional gastrointestinal disorders: Differences between functional dyspepsia, irritable bowel syndrome and overlap syndrome

Heon Jeong Lee, Sun Young Lee, Jeong Hwan Kim, In Kyung Sung, Hyung Seok Park, Choon Jo Jin, Seung Gul Kang, Hiejin Yoon, Hoon Jai Chun

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

Objective: To investigate the differences in depressive mood and quality of life in patients with between functional dyspepsia (FD), irritable bowel syndrome (IBS), and FD-IBS overlap as diagnosed based on Rome III criteria. Methods: The subjects completed a questionnaire based on Rome III criteria, the Beck Depressive Inventory (BDI) including Cognitive Depression Index (CDI) for depressive mood evaluation and the 36-item Short Form general health survey (SF-36) for quality of life assessment. Upper gastrointestinal endoscopy and colonoscopy were performed to exclude organic disease. Results: Of 279 subjects, 70 and 124 subjects were diagnosed as FD and IBS, respectively. FD-IBS overlap patients (n=42) and FD alone patients (n=28) showed higher BDI scores than normal subjects (n=127) (P<001 and P=02, respectively), whereas that of IBS alone patients (n=82) did not show difference (P=17). All the SF-36 subscores of the FD-IBS overlap patients were significantly lower than normal subjects (P<05). Conclusions: Depressive mood was significantly related to FD and FD-IBS overlap but not to IBS based on Rome III criteria. FD-IBS overlap patients have worse quality of life than FD-alone and IBS-alone patients.

Original languageEnglish
Pages (from-to)499-502
Number of pages4
JournalGeneral Hospital Psychiatry
Volume32
Issue number5
DOIs
Publication statusPublished - 2010 Sep

Keywords

  • Functional dyspepsia
  • Functional gastrointestinal disorder
  • Irritable bowel syndrome
  • Quality of life
  • Rome III

ASJC Scopus subject areas

  • Psychiatry and Mental health

Fingerprint Dive into the research topics of 'Depressive mood and quality of life in functional gastrointestinal disorders: Differences between functional dyspepsia, irritable bowel syndrome and overlap syndrome'. Together they form a unique fingerprint.

  • Cite this