Abstract
Objective: To investigate the differences in depressive mood and quality of life in patients with between functional dyspepsia (FD), irritable bowel syndrome (IBS), and FD-IBS overlap as diagnosed based on Rome III criteria. Methods: The subjects completed a questionnaire based on Rome III criteria, the Beck Depressive Inventory (BDI) including Cognitive Depression Index (CDI) for depressive mood evaluation and the 36-item Short Form general health survey (SF-36) for quality of life assessment. Upper gastrointestinal endoscopy and colonoscopy were performed to exclude organic disease. Results: Of 279 subjects, 70 and 124 subjects were diagnosed as FD and IBS, respectively. FD-IBS overlap patients (n=42) and FD alone patients (n=28) showed higher BDI scores than normal subjects (n=127) (P<001 and P=02, respectively), whereas that of IBS alone patients (n=82) did not show difference (P=17). All the SF-36 subscores of the FD-IBS overlap patients were significantly lower than normal subjects (P<05). Conclusions: Depressive mood was significantly related to FD and FD-IBS overlap but not to IBS based on Rome III criteria. FD-IBS overlap patients have worse quality of life than FD-alone and IBS-alone patients.
| Original language | English |
|---|---|
| Pages (from-to) | 499-502 |
| Number of pages | 4 |
| Journal | General Hospital Psychiatry |
| Volume | 32 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - 2010 Sep 1 |
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Keywords
- Functional dyspepsia
- Functional gastrointestinal disorder
- Irritable bowel syndrome
- Quality of life
- Rome III
ASJC Scopus subject areas
- Psychiatry and Mental health
Cite this
Depressive mood and quality of life in functional gastrointestinal disorders : Differences between functional dyspepsia, irritable bowel syndrome and overlap syndrome. / Lee, Heon-Jeong; Lee, Sun Young; Kim, Jeong Hwan; Sung, In Kyung; Park, Hyung Seok; Jin, Choon Jo; Kang, Seung Gul; Yoon, Hiejin; Chun, Hoon-Jai.
In: General Hospital Psychiatry, Vol. 32, No. 5, 01.09.2010, p. 499-502.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Depressive mood and quality of life in functional gastrointestinal disorders
T2 - Differences between functional dyspepsia, irritable bowel syndrome and overlap syndrome
AU - Lee, Heon-Jeong
AU - Lee, Sun Young
AU - Kim, Jeong Hwan
AU - Sung, In Kyung
AU - Park, Hyung Seok
AU - Jin, Choon Jo
AU - Kang, Seung Gul
AU - Yoon, Hiejin
AU - Chun, Hoon-Jai
PY - 2010/9/1
Y1 - 2010/9/1
N2 - Objective: To investigate the differences in depressive mood and quality of life in patients with between functional dyspepsia (FD), irritable bowel syndrome (IBS), and FD-IBS overlap as diagnosed based on Rome III criteria. Methods: The subjects completed a questionnaire based on Rome III criteria, the Beck Depressive Inventory (BDI) including Cognitive Depression Index (CDI) for depressive mood evaluation and the 36-item Short Form general health survey (SF-36) for quality of life assessment. Upper gastrointestinal endoscopy and colonoscopy were performed to exclude organic disease. Results: Of 279 subjects, 70 and 124 subjects were diagnosed as FD and IBS, respectively. FD-IBS overlap patients (n=42) and FD alone patients (n=28) showed higher BDI scores than normal subjects (n=127) (P<001 and P=02, respectively), whereas that of IBS alone patients (n=82) did not show difference (P=17). All the SF-36 subscores of the FD-IBS overlap patients were significantly lower than normal subjects (P<05). Conclusions: Depressive mood was significantly related to FD and FD-IBS overlap but not to IBS based on Rome III criteria. FD-IBS overlap patients have worse quality of life than FD-alone and IBS-alone patients.
AB - Objective: To investigate the differences in depressive mood and quality of life in patients with between functional dyspepsia (FD), irritable bowel syndrome (IBS), and FD-IBS overlap as diagnosed based on Rome III criteria. Methods: The subjects completed a questionnaire based on Rome III criteria, the Beck Depressive Inventory (BDI) including Cognitive Depression Index (CDI) for depressive mood evaluation and the 36-item Short Form general health survey (SF-36) for quality of life assessment. Upper gastrointestinal endoscopy and colonoscopy were performed to exclude organic disease. Results: Of 279 subjects, 70 and 124 subjects were diagnosed as FD and IBS, respectively. FD-IBS overlap patients (n=42) and FD alone patients (n=28) showed higher BDI scores than normal subjects (n=127) (P<001 and P=02, respectively), whereas that of IBS alone patients (n=82) did not show difference (P=17). All the SF-36 subscores of the FD-IBS overlap patients were significantly lower than normal subjects (P<05). Conclusions: Depressive mood was significantly related to FD and FD-IBS overlap but not to IBS based on Rome III criteria. FD-IBS overlap patients have worse quality of life than FD-alone and IBS-alone patients.
KW - Functional dyspepsia
KW - Functional gastrointestinal disorder
KW - Irritable bowel syndrome
KW - Quality of life
KW - Rome III
UR - http://www.scopus.com/inward/record.url?scp=77956875929&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77956875929&partnerID=8YFLogxK
U2 - 10.1016/j.genhosppsych.2010.05.002
DO - 10.1016/j.genhosppsych.2010.05.002
M3 - Article
VL - 32
SP - 499
EP - 502
JO - General Hospital Psychiatry
JF - General Hospital Psychiatry
SN - 0163-8343
IS - 5
ER -