Depressive mood and quality of life in functional gastrointestinal disorders: Differences between functional dyspepsia, irritable bowel syndrome and overlap syndrome

Heon-Jeong Lee, Sun Young Lee, Jeong Hwan Kim, In Kyung Sung, Hyung Seok Park, Choon Jo Jin, Seung Gul Kang, Hiejin Yoon, Hoon-Jai Chun

Research output: Contribution to journalArticle

35 Citations (Scopus)

Abstract

Objective: To investigate the differences in depressive mood and quality of life in patients with between functional dyspepsia (FD), irritable bowel syndrome (IBS), and FD-IBS overlap as diagnosed based on Rome III criteria. Methods: The subjects completed a questionnaire based on Rome III criteria, the Beck Depressive Inventory (BDI) including Cognitive Depression Index (CDI) for depressive mood evaluation and the 36-item Short Form general health survey (SF-36) for quality of life assessment. Upper gastrointestinal endoscopy and colonoscopy were performed to exclude organic disease. Results: Of 279 subjects, 70 and 124 subjects were diagnosed as FD and IBS, respectively. FD-IBS overlap patients (n=42) and FD alone patients (n=28) showed higher BDI scores than normal subjects (n=127) (P<001 and P=02, respectively), whereas that of IBS alone patients (n=82) did not show difference (P=17). All the SF-36 subscores of the FD-IBS overlap patients were significantly lower than normal subjects (P<05). Conclusions: Depressive mood was significantly related to FD and FD-IBS overlap but not to IBS based on Rome III criteria. FD-IBS overlap patients have worse quality of life than FD-alone and IBS-alone patients.

Original languageEnglish
Pages (from-to)499-502
Number of pages4
JournalGeneral Hospital Psychiatry
Volume32
Issue number5
DOIs
Publication statusPublished - 2010 Sep 1

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Irritable Bowel Syndrome
Gastrointestinal Diseases
Dyspepsia
Quality of Life
Equipment and Supplies
Gastrointestinal Endoscopy
Colonoscopy
Health Surveys
Depression

Keywords

  • Functional dyspepsia
  • Functional gastrointestinal disorder
  • Irritable bowel syndrome
  • Quality of life
  • Rome III

ASJC Scopus subject areas

  • Psychiatry and Mental health

Cite this

Depressive mood and quality of life in functional gastrointestinal disorders : Differences between functional dyspepsia, irritable bowel syndrome and overlap syndrome. / Lee, Heon-Jeong; Lee, Sun Young; Kim, Jeong Hwan; Sung, In Kyung; Park, Hyung Seok; Jin, Choon Jo; Kang, Seung Gul; Yoon, Hiejin; Chun, Hoon-Jai.

In: General Hospital Psychiatry, Vol. 32, No. 5, 01.09.2010, p. 499-502.

Research output: Contribution to journalArticle

Lee, Heon-Jeong ; Lee, Sun Young ; Kim, Jeong Hwan ; Sung, In Kyung ; Park, Hyung Seok ; Jin, Choon Jo ; Kang, Seung Gul ; Yoon, Hiejin ; Chun, Hoon-Jai. / Depressive mood and quality of life in functional gastrointestinal disorders : Differences between functional dyspepsia, irritable bowel syndrome and overlap syndrome. In: General Hospital Psychiatry. 2010 ; Vol. 32, No. 5. pp. 499-502.
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