Design of molecular two-photon probes for in vivo imaging. 2H-Benzo[h]chromene-2-one derivatives

Hwan Myung Kim, Xing Zhong Fang, Pil Rye Yang, Jae Sung Yi, Young-Gyu Ko, Ming Jun Piao, Young Dae Chung, Young Woo Park, Seung-Joon Jeon, Bong-Rae Cho

Research output: Contribution to journalArticle

50 Citations (Scopus)

Abstract

2H-Benzo[h]chromene-2-one derivatives showing appreciable water solubility, significant two-photon cross sections, high photostability, cell permeability, low toxicity, and ability to be converted to a protein TP probe have been developed by incorporating all of the needed functions within a small molecule.

Original languageEnglish
Pages (from-to)2791-2795
Number of pages5
JournalTetrahedron Letters
Volume48
Issue number15
DOIs
Publication statusPublished - 2007 Apr 9

Fingerprint

Benzopyrans
Photons
Solubility
Toxicity
Permeability
Derivatives
Imaging techniques
Molecules
Water
Proteins

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Design of molecular two-photon probes for in vivo imaging. 2H-Benzo[h]chromene-2-one derivatives. / Kim, Hwan Myung; Fang, Xing Zhong; Yang, Pil Rye; Yi, Jae Sung; Ko, Young-Gyu; Piao, Ming Jun; Chung, Young Dae; Park, Young Woo; Jeon, Seung-Joon; Cho, Bong-Rae.

In: Tetrahedron Letters, Vol. 48, No. 15, 09.04.2007, p. 2791-2795.

Research output: Contribution to journalArticle

Kim, Hwan Myung ; Fang, Xing Zhong ; Yang, Pil Rye ; Yi, Jae Sung ; Ko, Young-Gyu ; Piao, Ming Jun ; Chung, Young Dae ; Park, Young Woo ; Jeon, Seung-Joon ; Cho, Bong-Rae. / Design of molecular two-photon probes for in vivo imaging. 2H-Benzo[h]chromene-2-one derivatives. In: Tetrahedron Letters. 2007 ; Vol. 48, No. 15. pp. 2791-2795.
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