Design of molecular two-photon probes for in vivo imaging. 2H-Benzo[h]chromene-2-one derivatives

Hwan Myung Kim, Xing Zhong Fang, Pil Rye Yang, Jae Sung Yi, Young Gyu Ko, Ming Jun Piao, Young Dae Chung, Young Woo Park, Seung Joon Jeon, Bong Rae Cho

Research output: Contribution to journalArticle

52 Citations (Scopus)

Abstract

2H-Benzo[h]chromene-2-one derivatives showing appreciable water solubility, significant two-photon cross sections, high photostability, cell permeability, low toxicity, and ability to be converted to a protein TP probe have been developed by incorporating all of the needed functions within a small molecule.

Original languageEnglish
Pages (from-to)2791-2795
Number of pages5
JournalTetrahedron Letters
Volume48
Issue number15
DOIs
Publication statusPublished - 2007 Apr 9

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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