Detection of small neutral carbohydrates using various supporting materials in laser desorption/ionization mass spectrometry

Hyo Jik Yang, Aera Lee, Myung Ki Lee, Woong Kim, Jeongkwon Kim

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

A comprehensive comparative investigation of small carbohydrates in laser desorption ionization was performed on supporting materials composed of sodiated 2,5-dihydroxybenzoic acid (DHB), carbon nanotubes, an ionic liquid matrix of DHB-pyridine, a binary matrix of DHB-aminopyrazine, zinc oxide nanoparticles, and gold nanoparticles. The abundance of [M+Na]+ ions, where M is glucose or sucrose, was compared for each supporting material. The highest sensitivity for both glucose and sucrose, with a detection limit of 3 pmol, was observed with carbon nanotubes. Both carbon nanotubes and the ionic liquid matrix exhibited the highest reproducibility.

Original languageEnglish
Pages (from-to)35-40
Number of pages6
JournalBulletin of the Korean Chemical Society
Volume31
Issue number1
DOIs
Publication statusPublished - 2010 Jan 1

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Keywords

  • Binary matrix
  • Carbohydrate
  • Ionic liquid matrix
  • Laser desorption ionization
  • MALDI

ASJC Scopus subject areas

  • Chemistry(all)

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