TY - JOUR
T1 - Detection of small neutral carbohydrates using various supporting materials in laser desorption/ionization mass spectrometry
AU - Yang, Hyo Jik
AU - Lee, Aera
AU - Lee, Myung Ki
AU - Kim, Woong
AU - Kim, Jeongkwon
N1 - Copyright:
Copyright 2010 Elsevier B.V., All rights reserved.
PY - 2010/1
Y1 - 2010/1
N2 - A comprehensive comparative investigation of small carbohydrates in laser desorption ionization was performed on supporting materials composed of sodiated 2,5-dihydroxybenzoic acid (DHB), carbon nanotubes, an ionic liquid matrix of DHB-pyridine, a binary matrix of DHB-aminopyrazine, zinc oxide nanoparticles, and gold nanoparticles. The abundance of [M+Na]+ ions, where M is glucose or sucrose, was compared for each supporting material. The highest sensitivity for both glucose and sucrose, with a detection limit of 3 pmol, was observed with carbon nanotubes. Both carbon nanotubes and the ionic liquid matrix exhibited the highest reproducibility.
AB - A comprehensive comparative investigation of small carbohydrates in laser desorption ionization was performed on supporting materials composed of sodiated 2,5-dihydroxybenzoic acid (DHB), carbon nanotubes, an ionic liquid matrix of DHB-pyridine, a binary matrix of DHB-aminopyrazine, zinc oxide nanoparticles, and gold nanoparticles. The abundance of [M+Na]+ ions, where M is glucose or sucrose, was compared for each supporting material. The highest sensitivity for both glucose and sucrose, with a detection limit of 3 pmol, was observed with carbon nanotubes. Both carbon nanotubes and the ionic liquid matrix exhibited the highest reproducibility.
KW - Binary matrix
KW - Carbohydrate
KW - Ionic liquid matrix
KW - Laser desorption ionization
KW - MALDI
UR - http://www.scopus.com/inward/record.url?scp=77951796528&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77951796528&partnerID=8YFLogxK
U2 - 10.5012/bkcs.2010.31.01.035
DO - 10.5012/bkcs.2010.31.01.035
M3 - Article
AN - SCOPUS:77951796528
VL - 31
SP - 35
EP - 40
JO - Bulletin of the Korean Chemical Society
JF - Bulletin of the Korean Chemical Society
SN - 0253-2964
IS - 1
ER -