Development and analysis of a microfluidic photothermal absorbance detector using polyelectrolytic gel electrodes

Honggu Chun, Patty J. Dennis, Erin R. Ferguson, Jean Pierre Alarie, James W. Jorgenson, J. Michael Ramsey

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Abstract

We report on a sensitive photothermal absorbance detection method for use with a microfluidic chip using polyelectrolytic gel electrodes (PGEs). PGEs are microfabricated into glass substrates by photopolymerization, enabling contact measurement of conductivity without suffering redox effects from the application of a high electric field. Photothermal techniques involve heating of the solution through the radiationless relaxation of optically excited states, which subsequently results in a change in the solution viscosity. The microfluidic based photothermal system monitors the solution viscosity by measuring changes in conductivity. Experimental factors including laser modulation frequency, and laser power were studied. In addition, an electrokinetic separation of potassium, DABSYL-tagged glucosamine (DABSYLGlu) has been demonstrated.

Original languageEnglish
Title of host publication12th International Conference on Miniaturized Systems for Chemistry and Life Sciences - The Proceedings of MicroTAS 2008 Conference
PublisherChemical and Biological Microsystems Society
Pages934-936
Number of pages3
Publication statusPublished - 2008 Jan 1
Externally publishedYes
Event12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 - San Diego, CA, United States
Duration: 2008 Oct 122008 Oct 16

Other

Other12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008
CountryUnited States
CitySan Diego, CA
Period08/10/1208/10/16

ASJC Scopus subject areas

  • Chemical Engineering (miscellaneous)
  • Bioengineering

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  • Cite this

    Chun, H., Dennis, P. J., Ferguson, E. R., Alarie, J. P., Jorgenson, J. W., & Ramsey, J. M. (2008). Development and analysis of a microfluidic photothermal absorbance detector using polyelectrolytic gel electrodes. In 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences - The Proceedings of MicroTAS 2008 Conference (pp. 934-936). Chemical and Biological Microsystems Society.