Development and evaluation of a protein microarray chip for diagnosis of hepatitis C virus

Chul Soo Yuk, Ku Lee Hyung, Tae Kim Hee, Keel Choi Yong, Byung Cheon Lee, Bok Hwan Chun, Namhyun Chung

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

A protein chip diagnostic kit was developed for the diagnosis of hepatitis C virus (HCV) based on the protein chip technique and the immuno-concentration method. This kit was designed for low-density protein chips and also for the availability of multiple sample screening. Applicability of the chip was evaluated using 96 blood specimens and the results were compared to results of an anti-HCV enzyme immunoassay (EIA) test. With further development, the technology associated with the development of this chip could be applied to the simultaneous detection of multiple protein-protein, protein-ligand interactions.

Original languageEnglish
Pages (from-to)1563-1568
Number of pages6
JournalBiotechnology Letters
Volume26
Issue number20
DOIs
Publication statusPublished - 2004 Oct 1

Fingerprint

Protein Array Analysis
Microarrays
Viruses
Hepacivirus
Proteins
Immunoenzyme Techniques
Ligands
Technology
Screening
Blood
Enzymes
Availability

Keywords

  • Blood testing
  • Hepatitis C virus
  • Immuno-concentration
  • Membrane
  • Microarray
  • Protein array

ASJC Scopus subject areas

  • Biotechnology
  • Applied Microbiology and Biotechnology
  • Microbiology
  • Bioengineering

Cite this

Development and evaluation of a protein microarray chip for diagnosis of hepatitis C virus. / Yuk, Chul Soo; Hyung, Ku Lee; Hee, Tae Kim; Yong, Keel Choi; Lee, Byung Cheon; Chun, Bok Hwan; Chung, Namhyun.

In: Biotechnology Letters, Vol. 26, No. 20, 01.10.2004, p. 1563-1568.

Research output: Contribution to journalArticle

Yuk, Chul Soo ; Hyung, Ku Lee ; Hee, Tae Kim ; Yong, Keel Choi ; Lee, Byung Cheon ; Chun, Bok Hwan ; Chung, Namhyun. / Development and evaluation of a protein microarray chip for diagnosis of hepatitis C virus. In: Biotechnology Letters. 2004 ; Vol. 26, No. 20. pp. 1563-1568.
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