Development and growth of the normal cranial vault: An embryologic review

Sung Won Jin, Ki Bum Sim, Sang Dae Kim

    Research output: Contribution to journalReview articlepeer-review

    54 Citations (Scopus)

    Abstract

    Understanding the development of a skull deformity requires an understanding of the normal morphogenesis of the cranium. Craniosynostosis is the premature, pathologic ossification of one or more cranial sutures leading to skull deformities. A review of the English medical literature using textbooks and standard search engines was performed to gather information about the prenatal development and growth of the cranial vault of the neurocranium. A process of morphogenic sequencing begins during prenatal development and growth, continues postnatally, and contributes to the basis for the differential manner of growth of cranial vault bones. This improved knowledge might facilitate comprehension of the pathophysiology of craniosynostosis.

    Original languageEnglish
    Pages (from-to)192-196
    Number of pages5
    JournalJournal of Korean Neurosurgical Society
    Volume59
    Issue number3
    DOIs
    Publication statusPublished - 2016

    Keywords

    • Cranial sutures
    • Craniosynostosis
    • Embryonic development
    • Growth
    • Skull

    ASJC Scopus subject areas

    • Surgery
    • Neuroscience(all)
    • Clinical Neurology

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