Development of a microfluidic device for performing sample preconcentration and capillary electrophoresis separation

Honggu Chun, J. P. Alarie, J. M. Ramsey

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We report on a microfabricated device for sample preconcentration and capillary electrophoresis (CE) separation in a glass microchip. The device allows highly efficient anion-selective preconcentration to be performed with a micro-nano-microchannel structure. An integrated cross channel enables gate-injection of the preconcentrated sample into the analysis channel for CE separation. Sample preconcentration and corresponding enhanced CE separation signal have been demonstrated with TRITC-tagged peptides.

Original languageEnglish
Title of host publication14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010
Pages1727-1729
Number of pages3
Volume3
Publication statusPublished - 2010 Dec 1
Externally publishedYes
Event14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010 - Groningen, Netherlands
Duration: 2010 Oct 32010 Oct 7

Other

Other14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010
CountryNetherlands
CityGroningen
Period10/10/310/10/7

Fingerprint

Capillary electrophoresis
Microfluidics
Microchannels
Peptides
Negative ions
Glass

Keywords

  • Electrophoresis
  • Preconcentration
  • Separation

ASJC Scopus subject areas

  • Control and Systems Engineering

Cite this

Chun, H., Alarie, J. P., & Ramsey, J. M. (2010). Development of a microfluidic device for performing sample preconcentration and capillary electrophoresis separation. In 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010 (Vol. 3, pp. 1727-1729)

Development of a microfluidic device for performing sample preconcentration and capillary electrophoresis separation. / Chun, Honggu; Alarie, J. P.; Ramsey, J. M.

14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010. Vol. 3 2010. p. 1727-1729.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Chun, H, Alarie, JP & Ramsey, JM 2010, Development of a microfluidic device for performing sample preconcentration and capillary electrophoresis separation. in 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010. vol. 3, pp. 1727-1729, 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010, Groningen, Netherlands, 10/10/3.
Chun H, Alarie JP, Ramsey JM. Development of a microfluidic device for performing sample preconcentration and capillary electrophoresis separation. In 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010. Vol. 3. 2010. p. 1727-1729
Chun, Honggu ; Alarie, J. P. ; Ramsey, J. M. / Development of a microfluidic device for performing sample preconcentration and capillary electrophoresis separation. 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010. Vol. 3 2010. pp. 1727-1729
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