Development of a new pulsatile extracorporeal life support device incorporating a dual pulsatile blood pump

S. W. Choi, K. W. Nam, J. Chung, J. C. Lee, C. M. Hwang, Y. S. Won, Kyung Sun, Byoung Goo Min

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

A new pulsatile extracorporeal life support device (ECLS) has been developed, designed to sustain pulsatile blood flow during emergency cardiopulmonary resuscitations and cardiopulmonary operations. This device features two identical pulsatile pumps that operate alternately and can therefore provide blood inflow in a more uniform manner than similar systems featuring a single-pump configuration. In order to confirm the presumed benefits of this newly-developed dual pulsatile pump configuration, we have conducted a series of in vitro experiments designed to compare the properties of the new system with a single pump system, specifically with regard to pump delivery rate and active filling efficiency. Our results reveal that the dual pump configuration can, indeed, deliver a higher flow than can the single pump system, and exhibits an active filling efficiency superior to that of the single-pump configuration. We performed a series of animal experiments to measure the pulsatility of the dual-pump configuration in terms of equivalent energy pressure (EEP). In order to measure EEP, we measured femoral arterial pressure and pump outflow. The results of our animal experiments revealed that the newly-developed pulstile ECLS exhibits sufficient pulsatility in terms of the EEP considerations.

Original languageEnglish
Pages (from-to)583-590
Number of pages8
JournalInternational Journal of Artificial Organs
Volume29
Issue number6
Publication statusPublished - 2006 Jun 1

Fingerprint

Extracorporeal Membrane Oxygenation
Blood
Pumps
Pressure
Equipment and Supplies
Pulsatile Flow
Cardiopulmonary Resuscitation
Thigh
Arterial Pressure
Emergencies
Animals
Resuscitation
Experiments

Keywords

  • Dual pulsatile pump
  • Equivalent energy pressure (EEP)
  • Extracorporeal life support device (ECLS)

ASJC Scopus subject areas

  • Bioengineering
  • Medicine (miscellaneous)
  • Biomaterials
  • Biomedical Engineering

Cite this

Choi, S. W., Nam, K. W., Chung, J., Lee, J. C., Hwang, C. M., Won, Y. S., ... Min, B. G. (2006). Development of a new pulsatile extracorporeal life support device incorporating a dual pulsatile blood pump. International Journal of Artificial Organs, 29(6), 583-590.

Development of a new pulsatile extracorporeal life support device incorporating a dual pulsatile blood pump. / Choi, S. W.; Nam, K. W.; Chung, J.; Lee, J. C.; Hwang, C. M.; Won, Y. S.; Sun, Kyung; Min, Byoung Goo.

In: International Journal of Artificial Organs, Vol. 29, No. 6, 01.06.2006, p. 583-590.

Research output: Contribution to journalArticle

Choi, SW, Nam, KW, Chung, J, Lee, JC, Hwang, CM, Won, YS, Sun, K & Min, BG 2006, 'Development of a new pulsatile extracorporeal life support device incorporating a dual pulsatile blood pump', International Journal of Artificial Organs, vol. 29, no. 6, pp. 583-590.
Choi, S. W. ; Nam, K. W. ; Chung, J. ; Lee, J. C. ; Hwang, C. M. ; Won, Y. S. ; Sun, Kyung ; Min, Byoung Goo. / Development of a new pulsatile extracorporeal life support device incorporating a dual pulsatile blood pump. In: International Journal of Artificial Organs. 2006 ; Vol. 29, No. 6. pp. 583-590.
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