Development of a novel fluorescence probe capable of assessing the cytoplasmic entry of siderophore-based conjugates

Hyeon Seok Kim, Woon Young Song, Hak Joong Kim

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

A novel fluorescence probe capable of assessing the cytoplasmic entry of siderophore-based conjugates was synthesized and evaluated by photochemical characterization and cell-based assays. The specific responsiveness to the cytoplasmic entry of the probe was implemented by adopting a disulfide linker, whose cleavage under the reducing conditions of the cytoplasm induced the display of a distinctive fluorescence signal. This journal is

Original languageEnglish
Pages (from-to)73-76
Number of pages4
JournalOrganic and Biomolecular Chemistry
Volume13
Issue number1
DOIs
Publication statusPublished - 2015 Jan 7

    Fingerprint

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Biochemistry

Cite this