Development of a novel fluorescence probe capable of assessing the cytoplasmic entry of siderophore-based conjugates

Hyeon Seok Kim, Woon Young Song, Hak Joong Kim

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

A novel fluorescence probe capable of assessing the cytoplasmic entry of siderophore-based conjugates was synthesized and evaluated by photochemical characterization and cell-based assays. The specific responsiveness to the cytoplasmic entry of the probe was implemented by adopting a disulfide linker, whose cleavage under the reducing conditions of the cytoplasm induced the display of a distinctive fluorescence signal. This journal is

Original languageEnglish
Pages (from-to)73-76
Number of pages4
JournalOrganic and Biomolecular Chemistry
Volume13
Issue number1
DOIs
Publication statusPublished - 2015 Jan 7

Fingerprint

Siderophores
entry
Fluorescence
fluorescence
cytoplasm
probes
disulfides
Disulfides
cleavage
Assays
Cytoplasm
Display devices
cells

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Biochemistry

Cite this

Development of a novel fluorescence probe capable of assessing the cytoplasmic entry of siderophore-based conjugates. / Kim, Hyeon Seok; Song, Woon Young; Kim, Hak Joong.

In: Organic and Biomolecular Chemistry, Vol. 13, No. 1, 07.01.2015, p. 73-76.

Research output: Contribution to journalArticle

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