Abstract
In recent years, the verification of the three-dimensional (3-D) distribution of the absorbed dose in the tumor volume has been significantly considered in a radiation-therapy treatment plan. This study produced a polymer gel under a normoxic condition by using antioxidants, instead of using a polymer gel dosimeter, that can only be applied under a hypoxic condition using nitrogen gas. Also, this study investigated the characteristics of normoxic polymer gel for various compositions of the gel compound samples to produce practical polymer gels and composite polymer gels with five different compositions. Magnetic resonance images, R2 mapping images, dose-R2 response curves were analyzed for various composition ratios, and dose distributions. This study prepared polymer gels (Tetrakis hydroxymethyl phosphonium chloride-normoxic methacrylic acid-gelatin, TENOMAG) under a normoxic condition by using antioxidants and obtained a composition ratio that could be applied practically in clinics.
| Original language | English |
|---|---|
| Pages (from-to) | 1798-1804 |
| Number of pages | 7 |
| Journal | Journal of the Korean Physical Society |
| Volume | 51 |
| Issue number | 5 |
| Publication status | Published - 2007 Nov 1 |
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Keywords
- Dose-R2 response curve
- Normoxic polymer gel
- Radiotherapy
- Three-dimensional dosimeter
ASJC Scopus subject areas
- Physics and Astronomy(all)
Cite this
Development of a novel normoxic polymer gel dosimeter (TENOMAG). / Cho, Sam Ju; Shin, Dongho; Huh, Hyun Do; Lee, Sang Hoon; Lim, Sang Wook; Jang, Jisun; Cho, Kwang Hwan; Shin, Hun Joo; Kwon, Sooil; Yun, Hyong Geun; Yun, Sang Mo; Shin, Dong Oh; Yang, Dae-Sik; Park, Young Je; Kim, Chul Yong; Lee, Suk.
In: Journal of the Korean Physical Society, Vol. 51, No. 5, 01.11.2007, p. 1798-1804.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Development of a novel normoxic polymer gel dosimeter (TENOMAG)
AU - Cho, Sam Ju
AU - Shin, Dongho
AU - Huh, Hyun Do
AU - Lee, Sang Hoon
AU - Lim, Sang Wook
AU - Jang, Jisun
AU - Cho, Kwang Hwan
AU - Shin, Hun Joo
AU - Kwon, Sooil
AU - Yun, Hyong Geun
AU - Yun, Sang Mo
AU - Shin, Dong Oh
AU - Yang, Dae-Sik
AU - Park, Young Je
AU - Kim, Chul Yong
AU - Lee, Suk
PY - 2007/11/1
Y1 - 2007/11/1
N2 - In recent years, the verification of the three-dimensional (3-D) distribution of the absorbed dose in the tumor volume has been significantly considered in a radiation-therapy treatment plan. This study produced a polymer gel under a normoxic condition by using antioxidants, instead of using a polymer gel dosimeter, that can only be applied under a hypoxic condition using nitrogen gas. Also, this study investigated the characteristics of normoxic polymer gel for various compositions of the gel compound samples to produce practical polymer gels and composite polymer gels with five different compositions. Magnetic resonance images, R2 mapping images, dose-R2 response curves were analyzed for various composition ratios, and dose distributions. This study prepared polymer gels (Tetrakis hydroxymethyl phosphonium chloride-normoxic methacrylic acid-gelatin, TENOMAG) under a normoxic condition by using antioxidants and obtained a composition ratio that could be applied practically in clinics.
AB - In recent years, the verification of the three-dimensional (3-D) distribution of the absorbed dose in the tumor volume has been significantly considered in a radiation-therapy treatment plan. This study produced a polymer gel under a normoxic condition by using antioxidants, instead of using a polymer gel dosimeter, that can only be applied under a hypoxic condition using nitrogen gas. Also, this study investigated the characteristics of normoxic polymer gel for various compositions of the gel compound samples to produce practical polymer gels and composite polymer gels with five different compositions. Magnetic resonance images, R2 mapping images, dose-R2 response curves were analyzed for various composition ratios, and dose distributions. This study prepared polymer gels (Tetrakis hydroxymethyl phosphonium chloride-normoxic methacrylic acid-gelatin, TENOMAG) under a normoxic condition by using antioxidants and obtained a composition ratio that could be applied practically in clinics.
KW - Dose-R2 response curve
KW - Normoxic polymer gel
KW - Radiotherapy
KW - Three-dimensional dosimeter
UR - http://www.scopus.com/inward/record.url?scp=36849067867&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=36849067867&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:36849067867
VL - 51
SP - 1798
EP - 1804
JO - Journal of the Korean Physical Society
JF - Journal of the Korean Physical Society
SN - 0374-4884
IS - 5
ER -