TY - JOUR
T1 - Development of a subject-specific guide system for Low-Intensity Focused Ultrasound (LIFU) brain stimulation
AU - Joe, Haeyoung
AU - Pahk, Ki Joo
AU - Park, Shinsuk
AU - Kim, Hyungmin
N1 - Funding Information:
This research was supported by the Brain Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science, ICT & Future Planning ( 2015M3C7A1064833 ).
PY - 2019/7
Y1 - 2019/7
N2 - Low-Intensity Focused Ultrasound (LIFU) has recently been considered as a promising neuromodulation technique because it can noninvasively stimulate the brain with a high spatial resolution. As spatial resolution is improved, there is a growing demand for developing more accurate and convenient guide systems. Therefore, in the present study, we have developed and prototyped a 3D printed wearable subject-specific helmet for LIFU stimulation that is guaranteed to be accurate. The spatial relationship between the target position and the full-width at half-maximum (FWHM) of acoustic pressure of the transducer, i.e. focal volume, was compared using the conventional image-guided navigation system. According to the distribution of positional errors, the target position was located well within the focal volume.
AB - Low-Intensity Focused Ultrasound (LIFU) has recently been considered as a promising neuromodulation technique because it can noninvasively stimulate the brain with a high spatial resolution. As spatial resolution is improved, there is a growing demand for developing more accurate and convenient guide systems. Therefore, in the present study, we have developed and prototyped a 3D printed wearable subject-specific helmet for LIFU stimulation that is guaranteed to be accurate. The spatial relationship between the target position and the full-width at half-maximum (FWHM) of acoustic pressure of the transducer, i.e. focal volume, was compared using the conventional image-guided navigation system. According to the distribution of positional errors, the target position was located well within the focal volume.
KW - Brain stimulation
KW - Image-guided navigation
KW - Low-intensity focused ultrasound
KW - Subject-specific helmet
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U2 - 10.1016/j.cmpb.2019.05.001
DO - 10.1016/j.cmpb.2019.05.001
M3 - Article
C2 - 31200898
AN - SCOPUS:85065546315
VL - 176
SP - 105
EP - 110
JO - Computer Methods and Programs in Biomedicine
JF - Computer Methods and Programs in Biomedicine
SN - 0169-2607
ER -