Development of a subject-specific guide system for Low-Intensity Focused Ultrasound (LIFU) brain stimulation

Haeyoung Joe, Ki Joo Pahk, Shinsuk Park, Hyungmin Kim

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)


Low-Intensity Focused Ultrasound (LIFU) has recently been considered as a promising neuromodulation technique because it can noninvasively stimulate the brain with a high spatial resolution. As spatial resolution is improved, there is a growing demand for developing more accurate and convenient guide systems. Therefore, in the present study, we have developed and prototyped a 3D printed wearable subject-specific helmet for LIFU stimulation that is guaranteed to be accurate. The spatial relationship between the target position and the full-width at half-maximum (FWHM) of acoustic pressure of the transducer, i.e. focal volume, was compared using the conventional image-guided navigation system. According to the distribution of positional errors, the target position was located well within the focal volume.

Original languageEnglish
Pages (from-to)105-110
Number of pages6
JournalComputer Methods and Programs in Biomedicine
Publication statusPublished - 2019 Jul


  • Brain stimulation
  • Image-guided navigation
  • Low-intensity focused ultrasound
  • Subject-specific helmet

ASJC Scopus subject areas

  • Software
  • Computer Science Applications
  • Health Informatics


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