Development of a subject-specific guide system for Low-Intensity Focused Ultrasound (LIFU) brain stimulation

Haeyoung Joe; Ki Joo Pahk; Shin Suk Park; Hyungmin Kim

doi:10.1016/j.cmpb.2019.05.001

Development of a subject-specific guide system for Low-Intensity Focused Ultrasound (LIFU) brain stimulation

Haeyoung Joe, Ki Joo Pahk, Shin Suk Park, Hyungmin Kim

Department of Mechanical Engineering

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

Low-Intensity Focused Ultrasound (LIFU) has recently been considered as a promising neuromodulation technique because it can noninvasively stimulate the brain with a high spatial resolution. As spatial resolution is improved, there is a growing demand for developing more accurate and convenient guide systems. Therefore, in the present study, we have developed and prototyped a 3D printed wearable subject-specific helmet for LIFU stimulation that is guaranteed to be accurate. The spatial relationship between the target position and the full-width at half-maximum (FWHM) of acoustic pressure of the transducer, i.e. focal volume, was compared using the conventional image-guided navigation system. According to the distribution of positional errors, the target position was located well within the focal volume.

Original language	English
Pages (from-to)	105-110
Number of pages	6
Journal	Computer Methods and Programs in Biomedicine
Volume	176
DOIs	https://doi.org/10.1016/j.cmpb.2019.05.001
Publication status	Published - 2019 Jul 1

Keywords

Brain stimulation
Image-guided navigation
Low-intensity focused ultrasound
Subject-specific helmet

ASJC Scopus subject areas

Software
Computer Science Applications
Health Informatics

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abstract = "Low-Intensity Focused Ultrasound (LIFU) has recently been considered as a promising neuromodulation technique because it can noninvasively stimulate the brain with a high spatial resolution. As spatial resolution is improved, there is a growing demand for developing more accurate and convenient guide systems. Therefore, in the present study, we have developed and prototyped a 3D printed wearable subject-specific helmet for LIFU stimulation that is guaranteed to be accurate. The spatial relationship between the target position and the full-width at half-maximum (FWHM) of acoustic pressure of the transducer, i.e. focal volume, was compared using the conventional image-guided navigation system. According to the distribution of positional errors, the target position was located well within the focal volume.",

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