We developed an integrated home telemedicine system equipped with automatic diagnosis and consultation function for patients with chronic disease such as cardiac disease, respiratory disease, diabetes and hypertension. The system measures standard 12ch ECG, respiratory function, blood glucose level and noninvasive blood pressure (NIBP). The measured data were stored on the system and transmitted to the central server everyday through the internet. The system performed automatic diagnosis at every measurement and offered medical consultation to the patient If there was any abnormality in the diagnostic result, the system gave a real time alarm to the healthcare center for adequate teleconsultation or medical service. We have installed the developed system on an apartment for the performance evaluation and confirmed the possibility of the system as an effective tool for the telemedicine.