Traditional gamma cameras have large volume and heavy weight because of their large photomultiplier tube volume and low spatial resolution. Therefore, gamma cameras have the disadvantage of limited use due to their size and weight. In this study, we aim to reduce the total weight and size of the gamma camera for various applications. The proposed gamma camera uses a 3D metal printer to fabricate a collimator, and is designed to implement a high-resolution gamma camera using a discrete GAGG scintillator and SiPM array. The dimensions of the designed gamma camera are 86 × 65 × 78.5 mm3, and its weight is 934 g. The initial performance of the gamma camera design was first discovered as a measure of the preamplifier circuit with symmetric charge division. The data acquisition device used in the gamma camera was designed for various applications and can be expanded up to 16 channels. We also used the system on a chip field-programmable gate array for hardware and software flexibility. Currently, we are quantitatively studying the initial performance of the proposed compact gamma camera.