Development of MEMS-based cerebrospinal fluid shunt system

Seok Chung; Jung Kyung Kim; Kyu Chang Wang; Dong Chul Han; Jun Keun Chang

doi:10.1023/A:1027309830365

Development of MEMS-based cerebrospinal fluid shunt system

Seok Chung, Jung Kyung Kim, Kyu Chang Wang, Dong Chul Han, Jun Keun Chang

Research output: Contribution to journal › Article › peer-review

16 Citations (Scopus)

Abstract

We have developed a micro cerebrospinal fluid (CSF) shunt system with a MEMS-based micro CSF shunt valve. This valve consists of flow nozzles with membrane connected to anchor by bridges. The up-down movement of the membrane turns the CSF on and off, and the thickness and shape of bridges and membrane determine the valve characteristics, such as opening pressure. The membrane, anchor and bridges were made of micro patterned Parylene™ film. To make the membrane and bridge not be torn out in the CSF flow, we added a cover layer. The total dimension of the assembled CSF shunt valve is 2.5 × 2.5 mm² , and 0.8 mm in height. The burst pressure and flow rate of the valve were precisely controled by carefully selecting the design parameters, such as the thickness of membrane and bridge, and the width and number of the bridge. The developed CSF shunt system showed good performances in the evaluation test for commercialized CSF shunt systems.

Original language	English
Pages (from-to)	311-321
Number of pages	11
Journal	Biomedical Microdevices
Volume	5
Issue number	4
DOIs	https://doi.org/10.1023/A:1027309830365
Publication status	Published - 2003 Dec
Externally published	Yes

Keywords

Cerebrospinal fluid
MEMS
Parylene
Shunt system

ASJC Scopus subject areas

Biomedical Engineering
Molecular Biology

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10.1023/A:1027309830365

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title = "Development of MEMS-based cerebrospinal fluid shunt system",

abstract = "We have developed a micro cerebrospinal fluid (CSF) shunt system with a MEMS-based micro CSF shunt valve. This valve consists of flow nozzles with membrane connected to anchor by bridges. The up-down movement of the membrane turns the CSF on and off, and the thickness and shape of bridges and membrane determine the valve characteristics, such as opening pressure. The membrane, anchor and bridges were made of micro patterned Parylene{\texttrademark} film. To make the membrane and bridge not be torn out in the CSF flow, we added a cover layer. The total dimension of the assembled CSF shunt valve is 2.5 × 2.5 mm2 , and 0.8 mm in height. The burst pressure and flow rate of the valve were precisely controled by carefully selecting the design parameters, such as the thickness of membrane and bridge, and the width and number of the bridge. The developed CSF shunt system showed good performances in the evaluation test for commercialized CSF shunt systems.",

keywords = "Cerebrospinal fluid, MEMS, Parylene, Shunt system",

author = "Seok Chung and Kim, {Jung Kyung} and Wang, {Kyu Chang} and Han, {Dong Chul} and Chang, {Jun Keun}",

note = "Funding Information: This work was supported by the Milli-structure project granted from the Korean Institute of Industrial Technology and Ministry of Commerce, Industry and Energy. The authors give special thanks to Seung Ki Kim (Department of Neurosurgery, Seoul National University Hospital) for medical comments, and Jongwon Kim, Ph.D. (Biomedlab Co., Seoul, Korea) for CSF shunt case design and fabrication. Copyright: Copyright 2008 Elsevier B.V., All rights reserved.",

year = "2003",

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doi = "10.1023/A:1027309830365",

language = "English",

volume = "5",

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AU - Chung, Seok

AU - Kim, Jung Kyung

AU - Wang, Kyu Chang

AU - Han, Dong Chul

AU - Chang, Jun Keun

N1 - Funding Information: This work was supported by the Milli-structure project granted from the Korean Institute of Industrial Technology and Ministry of Commerce, Industry and Energy. The authors give special thanks to Seung Ki Kim (Department of Neurosurgery, Seoul National University Hospital) for medical comments, and Jongwon Kim, Ph.D. (Biomedlab Co., Seoul, Korea) for CSF shunt case design and fabrication. Copyright: Copyright 2008 Elsevier B.V., All rights reserved.

PY - 2003/12

Y1 - 2003/12

N2 - We have developed a micro cerebrospinal fluid (CSF) shunt system with a MEMS-based micro CSF shunt valve. This valve consists of flow nozzles with membrane connected to anchor by bridges. The up-down movement of the membrane turns the CSF on and off, and the thickness and shape of bridges and membrane determine the valve characteristics, such as opening pressure. The membrane, anchor and bridges were made of micro patterned Parylene™ film. To make the membrane and bridge not be torn out in the CSF flow, we added a cover layer. The total dimension of the assembled CSF shunt valve is 2.5 × 2.5 mm2 , and 0.8 mm in height. The burst pressure and flow rate of the valve were precisely controled by carefully selecting the design parameters, such as the thickness of membrane and bridge, and the width and number of the bridge. The developed CSF shunt system showed good performances in the evaluation test for commercialized CSF shunt systems.

AB - We have developed a micro cerebrospinal fluid (CSF) shunt system with a MEMS-based micro CSF shunt valve. This valve consists of flow nozzles with membrane connected to anchor by bridges. The up-down movement of the membrane turns the CSF on and off, and the thickness and shape of bridges and membrane determine the valve characteristics, such as opening pressure. The membrane, anchor and bridges were made of micro patterned Parylene™ film. To make the membrane and bridge not be torn out in the CSF flow, we added a cover layer. The total dimension of the assembled CSF shunt valve is 2.5 × 2.5 mm2 , and 0.8 mm in height. The burst pressure and flow rate of the valve were precisely controled by carefully selecting the design parameters, such as the thickness of membrane and bridge, and the width and number of the bridge. The developed CSF shunt system showed good performances in the evaluation test for commercialized CSF shunt systems.

KW - Cerebrospinal fluid

KW - MEMS

KW - Parylene

KW - Shunt system

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Development of MEMS-based cerebrospinal fluid shunt system

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Keywords

ASJC Scopus subject areas

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