Development of new cardiac deformity indexes for pectus excavatum on computed tomography: Feasibility for pre- and post-operative evaluation

Miyoung Kim, Ki Yeol Lee, Hyung Joo Park, Hee Young Kim, Eun-Young Kang, Yu Whan Oh, Bo Kyoung Seo, Bo-Kyung Je, Eun Jung Choi

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Purpose: The aim of this study was to evaluate new cardiac deformity indexes (CDIs) for diagnosis of pectus excavatum as well as morphological assessment of heart on computed tomography (CT). Materials and Methods: We retrospectively evaluated the CT images of the control group (n=200), and the pectus excavatum before and after correction groups (n=178), and calculated the CDIs; cardiac compression index (CCI), and cardiac asymmetry index (CAI). We also calculated chest wall compression index (CWCI) and asymmetry index (CWAI) on the axial images. We performed logistic regression analysis using each index and age as predictor variables. Results: The CDIs (CCI and CAI) were significant (p < 0.05) in the diagnosis of pectus excavatum, regardless of age (p = 0.4033, p = 0.8113). The CWCI and CWAI were significant (p < 0.05) and significantly affected by age (p < 0.05). If we selected 1.82 as the cutoff of the CCI, the sensitivity and specificity were 99.4% and 98%, respectively. The following cutoffs and the sensitivity and specificity were obtained: 1.15 for the CAI gave 94.4% and 94.5%, 3.05 for the CWCI gave 92.1% and 92%, and 1 for the CWAI gave 62.4% and 65%, respectively. The CCI after repair improved from 2.83 ± 0.84 to 1.84 ± 0.33, while the CWCI improved from 4.49 ± 1.61 to 2.57 ± 0.44. Conclusion: CDIs such as the CCI and CAI may be potentially useful to detect and estimate repair for pectus excavatum.

Original languageEnglish
Pages (from-to)385-390
Number of pages6
JournalYonsei Medical Journal
Volume50
Issue number3
DOIs
Publication statusPublished - 2009 Jul 30

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Funnel Chest
Thoracic Wall
Tomography
Sensitivity and Specificity
Logistic Models
Regression Analysis
Control Groups

Keywords

  • Cardiac deformity index
  • CT scan
  • Minimally invasive repair of pectus excavatum (MIRPE)
  • Pectus excavatum

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Development of new cardiac deformity indexes for pectus excavatum on computed tomography : Feasibility for pre- and post-operative evaluation. / Kim, Miyoung; Lee, Ki Yeol; Park, Hyung Joo; Kim, Hee Young; Kang, Eun-Young; Oh, Yu Whan; Seo, Bo Kyoung; Je, Bo-Kyung; Choi, Eun Jung.

In: Yonsei Medical Journal, Vol. 50, No. 3, 30.07.2009, p. 385-390.

Research output: Contribution to journalArticle

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title = "Development of new cardiac deformity indexes for pectus excavatum on computed tomography: Feasibility for pre- and post-operative evaluation",
abstract = "Purpose: The aim of this study was to evaluate new cardiac deformity indexes (CDIs) for diagnosis of pectus excavatum as well as morphological assessment of heart on computed tomography (CT). Materials and Methods: We retrospectively evaluated the CT images of the control group (n=200), and the pectus excavatum before and after correction groups (n=178), and calculated the CDIs; cardiac compression index (CCI), and cardiac asymmetry index (CAI). We also calculated chest wall compression index (CWCI) and asymmetry index (CWAI) on the axial images. We performed logistic regression analysis using each index and age as predictor variables. Results: The CDIs (CCI and CAI) were significant (p < 0.05) in the diagnosis of pectus excavatum, regardless of age (p = 0.4033, p = 0.8113). The CWCI and CWAI were significant (p < 0.05) and significantly affected by age (p < 0.05). If we selected 1.82 as the cutoff of the CCI, the sensitivity and specificity were 99.4{\%} and 98{\%}, respectively. The following cutoffs and the sensitivity and specificity were obtained: 1.15 for the CAI gave 94.4{\%} and 94.5{\%}, 3.05 for the CWCI gave 92.1{\%} and 92{\%}, and 1 for the CWAI gave 62.4{\%} and 65{\%}, respectively. The CCI after repair improved from 2.83 ± 0.84 to 1.84 ± 0.33, while the CWCI improved from 4.49 ± 1.61 to 2.57 ± 0.44. Conclusion: CDIs such as the CCI and CAI may be potentially useful to detect and estimate repair for pectus excavatum.",
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author = "Miyoung Kim and Lee, {Ki Yeol} and Park, {Hyung Joo} and Kim, {Hee Young} and Eun-Young Kang and Oh, {Yu Whan} and Seo, {Bo Kyoung} and Bo-Kyung Je and Choi, {Eun Jung}",
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T2 - Feasibility for pre- and post-operative evaluation

AU - Kim, Miyoung

AU - Lee, Ki Yeol

AU - Park, Hyung Joo

AU - Kim, Hee Young

AU - Kang, Eun-Young

AU - Oh, Yu Whan

AU - Seo, Bo Kyoung

AU - Je, Bo-Kyung

AU - Choi, Eun Jung

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AB - Purpose: The aim of this study was to evaluate new cardiac deformity indexes (CDIs) for diagnosis of pectus excavatum as well as morphological assessment of heart on computed tomography (CT). Materials and Methods: We retrospectively evaluated the CT images of the control group (n=200), and the pectus excavatum before and after correction groups (n=178), and calculated the CDIs; cardiac compression index (CCI), and cardiac asymmetry index (CAI). We also calculated chest wall compression index (CWCI) and asymmetry index (CWAI) on the axial images. We performed logistic regression analysis using each index and age as predictor variables. Results: The CDIs (CCI and CAI) were significant (p < 0.05) in the diagnosis of pectus excavatum, regardless of age (p = 0.4033, p = 0.8113). The CWCI and CWAI were significant (p < 0.05) and significantly affected by age (p < 0.05). If we selected 1.82 as the cutoff of the CCI, the sensitivity and specificity were 99.4% and 98%, respectively. The following cutoffs and the sensitivity and specificity were obtained: 1.15 for the CAI gave 94.4% and 94.5%, 3.05 for the CWCI gave 92.1% and 92%, and 1 for the CWAI gave 62.4% and 65%, respectively. The CCI after repair improved from 2.83 ± 0.84 to 1.84 ± 0.33, while the CWCI improved from 4.49 ± 1.61 to 2.57 ± 0.44. Conclusion: CDIs such as the CCI and CAI may be potentially useful to detect and estimate repair for pectus excavatum.

KW - Cardiac deformity index

KW - CT scan

KW - Minimally invasive repair of pectus excavatum (MIRPE)

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