Development of prediction equation of diffusing capacity of lung for koreans

Yong Il Hwang, Yong Bum Park, Hyoung Kyu Yoon, Seong Yong Lim, Tae Hyung Kim, Joo Hun Park, Won Yeon Lee, Seong Ju Park, Sei Won Lee, Woo Jin Kim, Ki Uk Kim, Kyeong Cheol Shin, Do Jin Kim, Hui Jung Kim, Tae Eun Kim, Kwang Ha Yoo, Jae Jeong Shim

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Abstract

Background: The diffusing capacity of the lung is influenced by multiple factors such as age, sex, height, weight, ethnicity and smoking status. Although a prediction equation for the diffusing capacity of Korea was proposed in the mid-1980s, this equation is not used currently. The aim of this study was to develop a new prediction equation for the diffusing capacity for Koreans. Methods: Using the data of the Korean National Health and Nutrition Examination Survey, a total of 140 nonsmokers with normal chest X-rays were enrolled in this study. Results: Using linear regression analysis, a new predicting equation for diffusing capacity was developed. For men, the following new equations were developed: carbon monoxide diffusing capacity (DLco)=–10.4433–0.1434×age (year)+0.2482×heights (cm); DLco/alveolar volume (VA)=6.01507–0.02374×age (year)–0.00233×heights (cm). For women the prediction equations were described as followed: DLco=–12.8895–0.0532×age (year)+0.2145×heights (cm) and DLco/VA=7.69516–0.02219×age (year)–0.01377×heights (cm). All equations were internally validated by k-fold cross validation method. Conclusion: In this study, we developed new prediction equations for the diffusing capacity of the lungs of Koreans. A further study is needed to validate the new predicting equation for diffusing capacity.

Original languageEnglish
Pages (from-to)42-48
Number of pages7
JournalTuberculosis and Respiratory Diseases
Volume81
Issue number1
DOIs
Publication statusPublished - 2018 Jan 1

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Keywords

  • Carbon Monoxide
  • Diffusion
  • Korean
  • Pulmonary Diffusing Capacity

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Infectious Diseases

Cite this

Hwang, Y. I., Park, Y. B., Yoon, H. K., Lim, S. Y., Kim, T. H., Park, J. H., Lee, W. Y., Park, S. J., Lee, S. W., Kim, W. J., Kim, K. U., Shin, K. C., Kim, D. J., Kim, H. J., Kim, T. E., Yoo, K. H., & Shim, J. J. (2018). Development of prediction equation of diffusing capacity of lung for koreans. Tuberculosis and Respiratory Diseases, 81(1), 42-48. https://doi.org/10.4046/trd.2017.0118