Abstract
Cystic lung disease (CLD) is a group of lung disorders characterized by the presence of multiple cysts, defined as air-filled lucencies or low-attenuating areas, bordered by a thin wall (usually < 2 mm). The recognition of CLDs has increased with the widespread use of computed tomography. This article addresses the mechanisms of cyst formation and the diagnostic approaches to CLDs. A number of assessment methods that can be used to confirm CLDs are discussed, including high-resolution computed tomography, pathologic approaches, and genetic/ serologic markers, together with treatment modalities, including new therapeutic drugs currently being evaluated. The CLDs covered by this review are lymphangioleiomyomatosis, pulmonary Langerhans cell histiocytosis, Birt-Hogg-Dube syndrome, lymphocytic interstitial pneumonia/follicular bronchiolitis, and amyloidosis.
| Original language | English |
|---|---|
| Pages (from-to) | 229-238 |
| Number of pages | 10 |
| Journal | Korean Journal of Internal Medicine |
| Volume | 32 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 2017 Jan 1 |
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Keywords
- Birt-Hogg-Dube syndrome
- Cystic lung disease
- Histiocytosis
- Lang-erhans-cell
- Lymphangioleiomyomatosis
ASJC Scopus subject areas
- Internal Medicine
Cite this
Diagnosis and treatment of cystic lung disease. / Park, Sanghoon; Lee, Eun Joo.
In: Korean Journal of Internal Medicine, Vol. 32, No. 2, 01.01.2017, p. 229-238.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Diagnosis and treatment of cystic lung disease
AU - Park, Sanghoon
AU - Lee, Eun Joo
PY - 2017/1/1
Y1 - 2017/1/1
N2 - Cystic lung disease (CLD) is a group of lung disorders characterized by the presence of multiple cysts, defined as air-filled lucencies or low-attenuating areas, bordered by a thin wall (usually < 2 mm). The recognition of CLDs has increased with the widespread use of computed tomography. This article addresses the mechanisms of cyst formation and the diagnostic approaches to CLDs. A number of assessment methods that can be used to confirm CLDs are discussed, including high-resolution computed tomography, pathologic approaches, and genetic/ serologic markers, together with treatment modalities, including new therapeutic drugs currently being evaluated. The CLDs covered by this review are lymphangioleiomyomatosis, pulmonary Langerhans cell histiocytosis, Birt-Hogg-Dube syndrome, lymphocytic interstitial pneumonia/follicular bronchiolitis, and amyloidosis.
AB - Cystic lung disease (CLD) is a group of lung disorders characterized by the presence of multiple cysts, defined as air-filled lucencies or low-attenuating areas, bordered by a thin wall (usually < 2 mm). The recognition of CLDs has increased with the widespread use of computed tomography. This article addresses the mechanisms of cyst formation and the diagnostic approaches to CLDs. A number of assessment methods that can be used to confirm CLDs are discussed, including high-resolution computed tomography, pathologic approaches, and genetic/ serologic markers, together with treatment modalities, including new therapeutic drugs currently being evaluated. The CLDs covered by this review are lymphangioleiomyomatosis, pulmonary Langerhans cell histiocytosis, Birt-Hogg-Dube syndrome, lymphocytic interstitial pneumonia/follicular bronchiolitis, and amyloidosis.
KW - Birt-Hogg-Dube syndrome
KW - Cystic lung disease
KW - Histiocytosis
KW - Lang-erhans-cell
KW - Lymphangioleiomyomatosis
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UR - http://www.scopus.com/inward/citedby.url?scp=85014838254&partnerID=8YFLogxK
U2 - 10.3904/kjim.2016.242
DO - 10.3904/kjim.2016.242
M3 - Review article
C2 - 28264540
AN - SCOPUS:85014838254
VL - 32
SP - 229
EP - 238
JO - Korean Journal of Internal Medicine
JF - Korean Journal of Internal Medicine
SN - 0494-4712
IS - 2
ER -