Diagnosis and treatment of cystic lung disease

Sanghoon Park, Eun Joo Lee

    Research output: Contribution to journalReview articlepeer-review

    5 Citations (Scopus)


    Cystic lung disease (CLD) is a group of lung disorders characterized by the presence of multiple cysts, defined as air-filled lucencies or low-attenuating areas, bordered by a thin wall (usually < 2 mm). The recognition of CLDs has increased with the widespread use of computed tomography. This article addresses the mechanisms of cyst formation and the diagnostic approaches to CLDs. A number of assessment methods that can be used to confirm CLDs are discussed, including high-resolution computed tomography, pathologic approaches, and genetic/ serologic markers, together with treatment modalities, including new therapeutic drugs currently being evaluated. The CLDs covered by this review are lymphangioleiomyomatosis, pulmonary Langerhans cell histiocytosis, Birt-Hogg-Dube syndrome, lymphocytic interstitial pneumonia/follicular bronchiolitis, and amyloidosis.

    Original languageEnglish
    Pages (from-to)229-238
    Number of pages10
    JournalKorean Journal of Internal Medicine
    Issue number2
    Publication statusPublished - 2017


    • Birt-Hogg-Dube syndrome
    • Cystic lung disease
    • Histiocytosis
    • Lang-erhans-cell
    • Lymphangioleiomyomatosis

    ASJC Scopus subject areas

    • Internal Medicine


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