Diagnostic guideline of Crohn's disease

Byong Duk Ye, Byung Ik Jang, Yoon Tae Jeen, Kang Moon Lee, Joo Sung Kim, Suk Kyun Yang

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

Crohn's disease (CD) is a chronic inflammatory bowel disease (IBD) with uncertain etiopathogenesis. CD can involve any site of gastrointestinal tract from mouth to anus and is associated with serious complications such as bowel stricture, perforation, abscess, and fistula formation. The incidence and prevalence rates of CD in Korea are still low compared with those of Western countries, but are rapidly increasing during the past decades. The diagnosis of CD is a challenging issue in some clinical situations and it is often difficult to differentiate CD from intestinal tuberculosis or Behçet's enterocolitis which are more prevalent in Korea than in Western countries. Therefore, IBD Study Group of KASID has set out to establish the diagnostic guideline of CD in Korea. There is no single gold standard for the diagnosis of CD and diagnosis is made by clinical evaluation including detailed history, physical examination, and combination of endoscopic findings, histology, radiologic findings and laboratory investigations. The typical symptoms of CD are abdominal pain, diarrhea, and weight loss especially in late adolescence or early adulthood. Initial laboratory investigations include CBC, C-reactive protein, and serum chemistry. Ileocolonoscopy and biopsies are recommended as the first line procedures to establish the diagnosis. Typical endoscopic findings of CD are non-continuous distribution of longitudinal ulcers, cobblestone mucosal appearance, and aphthous ulcerations arranged in a longitudinal fashion. The evaluation of small bowel with small bowel follow-through is recommended for suspected CD to establish diagnosis and to determine the extent and location of disease. Focal and patchy chronic inflammation, focal crypt irregularity, and non-caseating granulomas are usual microscopic features of CD. This is the first Korean diagnostic guideline for CD and needs revision with further data on CD in Koreans.

Original languageEnglish
Pages (from-to)161-176
Number of pages16
JournalThe Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi
Volume53
Issue number3
Publication statusPublished - 2009 Mar 1
Externally publishedYes

Fingerprint

Crohn Disease
Guidelines
Korea
Inflammatory Bowel Diseases
Enterocolitis
Anal Canal
Granuloma
C-Reactive Protein
Abscess
Abdominal Pain
Physical Examination
Ulcer
Fistula
Mouth
Gastrointestinal Tract
Weight Loss
Diarrhea
Histology
Pathologic Constriction
Tuberculosis

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Ye, B. D., Jang, B. I., Jeen, Y. T., Lee, K. M., Kim, J. S., & Yang, S. K. (2009). Diagnostic guideline of Crohn's disease. The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 53(3), 161-176.

Diagnostic guideline of Crohn's disease. / Ye, Byong Duk; Jang, Byung Ik; Jeen, Yoon Tae; Lee, Kang Moon; Kim, Joo Sung; Yang, Suk Kyun.

In: The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, Vol. 53, No. 3, 01.03.2009, p. 161-176.

Research output: Contribution to journalArticle

Ye, BD, Jang, BI, Jeen, YT, Lee, KM, Kim, JS & Yang, SK 2009, 'Diagnostic guideline of Crohn's disease', The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, vol. 53, no. 3, pp. 161-176.
Ye, Byong Duk ; Jang, Byung Ik ; Jeen, Yoon Tae ; Lee, Kang Moon ; Kim, Joo Sung ; Yang, Suk Kyun. / Diagnostic guideline of Crohn's disease. In: The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi. 2009 ; Vol. 53, No. 3. pp. 161-176.
@article{be8a5fd84763470395c30a917f4058ef,
title = "Diagnostic guideline of Crohn's disease",
abstract = "Crohn's disease (CD) is a chronic inflammatory bowel disease (IBD) with uncertain etiopathogenesis. CD can involve any site of gastrointestinal tract from mouth to anus and is associated with serious complications such as bowel stricture, perforation, abscess, and fistula formation. The incidence and prevalence rates of CD in Korea are still low compared with those of Western countries, but are rapidly increasing during the past decades. The diagnosis of CD is a challenging issue in some clinical situations and it is often difficult to differentiate CD from intestinal tuberculosis or Beh{\cc}et's enterocolitis which are more prevalent in Korea than in Western countries. Therefore, IBD Study Group of KASID has set out to establish the diagnostic guideline of CD in Korea. There is no single gold standard for the diagnosis of CD and diagnosis is made by clinical evaluation including detailed history, physical examination, and combination of endoscopic findings, histology, radiologic findings and laboratory investigations. The typical symptoms of CD are abdominal pain, diarrhea, and weight loss especially in late adolescence or early adulthood. Initial laboratory investigations include CBC, C-reactive protein, and serum chemistry. Ileocolonoscopy and biopsies are recommended as the first line procedures to establish the diagnosis. Typical endoscopic findings of CD are non-continuous distribution of longitudinal ulcers, cobblestone mucosal appearance, and aphthous ulcerations arranged in a longitudinal fashion. The evaluation of small bowel with small bowel follow-through is recommended for suspected CD to establish diagnosis and to determine the extent and location of disease. Focal and patchy chronic inflammation, focal crypt irregularity, and non-caseating granulomas are usual microscopic features of CD. This is the first Korean diagnostic guideline for CD and needs revision with further data on CD in Koreans.",
author = "Ye, {Byong Duk} and Jang, {Byung Ik} and Jeen, {Yoon Tae} and Lee, {Kang Moon} and Kim, {Joo Sung} and Yang, {Suk Kyun}",
year = "2009",
month = "3",
day = "1",
language = "English",
volume = "53",
pages = "161--176",
journal = "The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi",
issn = "1598-9992",
publisher = "Korean Society of Gastroenterology",
number = "3",

}

TY - JOUR

T1 - Diagnostic guideline of Crohn's disease

AU - Ye, Byong Duk

AU - Jang, Byung Ik

AU - Jeen, Yoon Tae

AU - Lee, Kang Moon

AU - Kim, Joo Sung

AU - Yang, Suk Kyun

PY - 2009/3/1

Y1 - 2009/3/1

N2 - Crohn's disease (CD) is a chronic inflammatory bowel disease (IBD) with uncertain etiopathogenesis. CD can involve any site of gastrointestinal tract from mouth to anus and is associated with serious complications such as bowel stricture, perforation, abscess, and fistula formation. The incidence and prevalence rates of CD in Korea are still low compared with those of Western countries, but are rapidly increasing during the past decades. The diagnosis of CD is a challenging issue in some clinical situations and it is often difficult to differentiate CD from intestinal tuberculosis or Behçet's enterocolitis which are more prevalent in Korea than in Western countries. Therefore, IBD Study Group of KASID has set out to establish the diagnostic guideline of CD in Korea. There is no single gold standard for the diagnosis of CD and diagnosis is made by clinical evaluation including detailed history, physical examination, and combination of endoscopic findings, histology, radiologic findings and laboratory investigations. The typical symptoms of CD are abdominal pain, diarrhea, and weight loss especially in late adolescence or early adulthood. Initial laboratory investigations include CBC, C-reactive protein, and serum chemistry. Ileocolonoscopy and biopsies are recommended as the first line procedures to establish the diagnosis. Typical endoscopic findings of CD are non-continuous distribution of longitudinal ulcers, cobblestone mucosal appearance, and aphthous ulcerations arranged in a longitudinal fashion. The evaluation of small bowel with small bowel follow-through is recommended for suspected CD to establish diagnosis and to determine the extent and location of disease. Focal and patchy chronic inflammation, focal crypt irregularity, and non-caseating granulomas are usual microscopic features of CD. This is the first Korean diagnostic guideline for CD and needs revision with further data on CD in Koreans.

AB - Crohn's disease (CD) is a chronic inflammatory bowel disease (IBD) with uncertain etiopathogenesis. CD can involve any site of gastrointestinal tract from mouth to anus and is associated with serious complications such as bowel stricture, perforation, abscess, and fistula formation. The incidence and prevalence rates of CD in Korea are still low compared with those of Western countries, but are rapidly increasing during the past decades. The diagnosis of CD is a challenging issue in some clinical situations and it is often difficult to differentiate CD from intestinal tuberculosis or Behçet's enterocolitis which are more prevalent in Korea than in Western countries. Therefore, IBD Study Group of KASID has set out to establish the diagnostic guideline of CD in Korea. There is no single gold standard for the diagnosis of CD and diagnosis is made by clinical evaluation including detailed history, physical examination, and combination of endoscopic findings, histology, radiologic findings and laboratory investigations. The typical symptoms of CD are abdominal pain, diarrhea, and weight loss especially in late adolescence or early adulthood. Initial laboratory investigations include CBC, C-reactive protein, and serum chemistry. Ileocolonoscopy and biopsies are recommended as the first line procedures to establish the diagnosis. Typical endoscopic findings of CD are non-continuous distribution of longitudinal ulcers, cobblestone mucosal appearance, and aphthous ulcerations arranged in a longitudinal fashion. The evaluation of small bowel with small bowel follow-through is recommended for suspected CD to establish diagnosis and to determine the extent and location of disease. Focal and patchy chronic inflammation, focal crypt irregularity, and non-caseating granulomas are usual microscopic features of CD. This is the first Korean diagnostic guideline for CD and needs revision with further data on CD in Koreans.

UR - http://www.scopus.com/inward/record.url?scp=70449700150&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=70449700150&partnerID=8YFLogxK

M3 - Article

VL - 53

SP - 161

EP - 176

JO - The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi

JF - The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi

SN - 1598-9992

IS - 3

ER -