Dietary galacto-oligosaccharides improve skin health: A randomized double blind clinical trial

Yang Hee Hong, Un Jae Chang, Young Suk Kim, Eun Young Jung, Hyung Joo Suh

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Background and Objectives: To study the effects of galacto-oligosaccharides (GOS) on the skin, we investigated skin-related parameters in healthy adults who received GOS for 12 weeks. Methods and Study Design: This double-blind, randomized, placebo-controlled study included subjects divided into two groups (control and GOS) by stratified block randomization. The GOS group received 1.0 g of GOS twice a day, whereas the control group received only vehicle. Results: The results showed that the increase in corneometer values from baseline to week 12 was significantly greater in the GOS group than in the control group (6.91 vs 2.88 arbitrary units, p < 0.05). The transepidermal water loss (TEWL) in the GOS group was reduced significantly after 12 weeks of GOS treatment (20.1 g/h/m2 at baseline vs 17.5 g/h/m2 at week 12, p < 0.05). The differences in total and percentage of wrinkle areas between the two groups were statistically significant after 12 weeks of GOS treatment (p < 0.05). Conclusion: Our findings support that oral treatment with GOS is beneficial to the skin and present the possibility of new nutritional strategies for skin care.

Original languageEnglish
Pages (from-to)613-618
Number of pages6
JournalAsia Pacific Journal of Clinical Nutrition
Volume26
Issue number4
DOIs
Publication statusPublished - 2017 Jun 1

Fingerprint

Oligosaccharides
Clinical Trials
Skin
Health
Control Groups
Skin Care
Random Allocation
Therapeutics
Placebos
Water

Keywords

  • Galacto-oligosaccharide
  • Prebiotics
  • Probiotics
  • Skin hydration
  • Wrinkle

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Medicine(all)
  • Nutrition and Dietetics

Cite this

Dietary galacto-oligosaccharides improve skin health : A randomized double blind clinical trial. / Hong, Yang Hee; Chang, Un Jae; Kim, Young Suk; Jung, Eun Young; Suh, Hyung Joo.

In: Asia Pacific Journal of Clinical Nutrition, Vol. 26, No. 4, 01.06.2017, p. 613-618.

Research output: Contribution to journalArticle

Hong, Yang Hee ; Chang, Un Jae ; Kim, Young Suk ; Jung, Eun Young ; Suh, Hyung Joo. / Dietary galacto-oligosaccharides improve skin health : A randomized double blind clinical trial. In: Asia Pacific Journal of Clinical Nutrition. 2017 ; Vol. 26, No. 4. pp. 613-618.
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