Differential diagnosis of parkinsonism with visual inspection of posture and gait in the early stage

Seon Min Lee, Minjik Kim, Hye Mi Lee, Kyum Yil Kwon, Hee Tae Kim, Seong Beom Koh

    Research output: Contribution to journalArticlepeer-review

    4 Citations (Scopus)

    Abstract

    Background: Parkinson's disease (PD) differs from atypical parkinsonism in many clinical aspects. Principally, posture and gait are distinct features in the early stages of the disease; thus, these differences can be helpful in differential diagnosis. Methods: We analyzed videos of patients with PD or atypical parkinsonism. A total of 76 patients with early PD (n= 56) or atypical parkinsonism (n= 20) were included. Items related to posture and gait were classified into three categories (standing, gait and associated symptoms) and each sub-item was analyzed. Results: Asymmetric arm-swing (p= 0.004) and accompanying tremor (p= 0.016) were significant indicators of early-stage PD. Staggering gait (p= 0.007) and en-bloc turning (p= 0.026) were more common in atypical parkinsonism. Characteristics with a high odds-ratio for atypical parkinsonism were en-bloc turning (β= 8.475, p= 0.032) and normal arm-swing (β= 14.6084, p= 0.036). Conclusions: Visual inspection of gait and posture provides reliable clues in the differential diagnosis of parkinsonism.

    Original languageEnglish
    Pages (from-to)1138-1141
    Number of pages4
    JournalGait and Posture
    Volume39
    Issue number4
    DOIs
    Publication statusPublished - 2014 Apr

    Keywords

    • Arm-swing
    • Atypical parkinsonism
    • Early stage
    • Parkinson's disease

    ASJC Scopus subject areas

    • Biophysics
    • Orthopedics and Sports Medicine
    • Rehabilitation

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