Differential diagnosis of parkinsonism with visual inspection of posture and gait in the early stage

Seon Min Lee, Minjik Kim, Hye Mi Lee, Kyum Yil Kwon, Hee Tae Kim, Seong Beom Koh

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Background: Parkinson's disease (PD) differs from atypical parkinsonism in many clinical aspects. Principally, posture and gait are distinct features in the early stages of the disease; thus, these differences can be helpful in differential diagnosis. Methods: We analyzed videos of patients with PD or atypical parkinsonism. A total of 76 patients with early PD (n= 56) or atypical parkinsonism (n= 20) were included. Items related to posture and gait were classified into three categories (standing, gait and associated symptoms) and each sub-item was analyzed. Results: Asymmetric arm-swing (p= 0.004) and accompanying tremor (p= 0.016) were significant indicators of early-stage PD. Staggering gait (p= 0.007) and en-bloc turning (p= 0.026) were more common in atypical parkinsonism. Characteristics with a high odds-ratio for atypical parkinsonism were en-bloc turning (β= 8.475, p= 0.032) and normal arm-swing (β= 14.6084, p= 0.036). Conclusions: Visual inspection of gait and posture provides reliable clues in the differential diagnosis of parkinsonism.

Original languageEnglish
Pages (from-to)1138-1141
Number of pages4
JournalGait and Posture
Volume39
Issue number4
DOIs
Publication statusPublished - 2014 Apr

Keywords

  • Arm-swing
  • Atypical parkinsonism
  • Early stage
  • Parkinson's disease

ASJC Scopus subject areas

  • Biophysics
  • Orthopedics and Sports Medicine
  • Rehabilitation

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