Diffraction optical tomography using a quantitative phase imaging unit

Kyoohyun Kim, Zahid Yaqoob, Kyeoreh Lee, Jeon Woong Kang, Youngwoon Choi, Poorya Hosseini, Peter T.C. So, Yongkeun Park

Research output: Contribution to journalArticle

52 Citations (Scopus)

Abstract

A simple and practical method to measure three-dimensional (3-D) refractive index (RI) distributions of biological cells is presented. A common-path self-reference interferometry consisting of a compact set of polarizers is attached to a conventional inverted microscope equipped with a beam scanning unit, which can precisely measure multiple 2-D holograms of a sample with high phase stability for various illumination angles, from which accurate 3-D optical diffraction tomograms of the sample can be reconstructed. 3-D RI tomograms of nonbiological samples such as polystyrene microspheres, as well as biological samples including human red blood cells and breast cancer cells, are presented.

Original languageEnglish
Pages (from-to)6935-6938
Number of pages4
JournalOptics Letters
Volume39
Issue number24
DOIs
Publication statusPublished - 2014 Dec 15
Externally publishedYes

Fingerprint

Optical Tomography
Refractometry
tomography
Interferometry
Polystyrenes
Lighting
Microspheres
diffraction
Erythrocytes
refractivity
Breast Neoplasms
erythrocytes
polarizers
breast
polystyrene
interferometry
cancer
illumination
microscopes
scanning

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics

Cite this

Kim, K., Yaqoob, Z., Lee, K., Kang, J. W., Choi, Y., Hosseini, P., ... Park, Y. (2014). Diffraction optical tomography using a quantitative phase imaging unit. Optics Letters, 39(24), 6935-6938. https://doi.org/10.1364/OL.39.006935

Diffraction optical tomography using a quantitative phase imaging unit. / Kim, Kyoohyun; Yaqoob, Zahid; Lee, Kyeoreh; Kang, Jeon Woong; Choi, Youngwoon; Hosseini, Poorya; So, Peter T.C.; Park, Yongkeun.

In: Optics Letters, Vol. 39, No. 24, 15.12.2014, p. 6935-6938.

Research output: Contribution to journalArticle

Kim, K, Yaqoob, Z, Lee, K, Kang, JW, Choi, Y, Hosseini, P, So, PTC & Park, Y 2014, 'Diffraction optical tomography using a quantitative phase imaging unit', Optics Letters, vol. 39, no. 24, pp. 6935-6938. https://doi.org/10.1364/OL.39.006935
Kim, Kyoohyun ; Yaqoob, Zahid ; Lee, Kyeoreh ; Kang, Jeon Woong ; Choi, Youngwoon ; Hosseini, Poorya ; So, Peter T.C. ; Park, Yongkeun. / Diffraction optical tomography using a quantitative phase imaging unit. In: Optics Letters. 2014 ; Vol. 39, No. 24. pp. 6935-6938.
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