Dihydroxylation of 2-vinylaziridine

Efficient synthesis of D-ribo-phytosphingosine

Hyo Jae Yoon, Yong Woo Kim, Baeck Kyoung Lee, Won Koo Lee, Yongeun Kim, Hyun Joon Ha

Research output: Contribution to journalArticle

42 Citations (Scopus)

Abstract

An efficient and highly stereoselective synthesis of D-ribo-(2S,3S,4R)- phytosphingosine was accomplished in 62% overall yield starting from commercially available (2S)-hydroxymethylaziridine via osmium-catalyzed asymmetric dihydroxylation as a key step.

Original languageEnglish
Pages (from-to)79-81
Number of pages3
JournalChemical Communications
Issue number1
DOIs
Publication statusPublished - 2007 Jan 1
Externally publishedYes

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phytosphingosine
Osmium
D-ribo-phytosphingosine

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Dihydroxylation of 2-vinylaziridine : Efficient synthesis of D-ribo-phytosphingosine. / Yoon, Hyo Jae; Kim, Yong Woo; Lee, Baeck Kyoung; Lee, Won Koo; Kim, Yongeun; Ha, Hyun Joon.

In: Chemical Communications, No. 1, 01.01.2007, p. 79-81.

Research output: Contribution to journalArticle

Yoon, Hyo Jae ; Kim, Yong Woo ; Lee, Baeck Kyoung ; Lee, Won Koo ; Kim, Yongeun ; Ha, Hyun Joon. / Dihydroxylation of 2-vinylaziridine : Efficient synthesis of D-ribo-phytosphingosine. In: Chemical Communications. 2007 ; No. 1. pp. 79-81.
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