Dihydroxylation of 2-vinylaziridine: Efficient synthesis of D-ribo-phytosphingosine

Hyo Jae Yoon, Yong Woo Kim, Baeck Kyoung Lee, Won Koo Lee, Yongeun Kim, Hyun Joon Ha

Research output: Contribution to journalArticle

43 Citations (Scopus)

Abstract

An efficient and highly stereoselective synthesis of D-ribo-(2S,3S,4R)- phytosphingosine was accomplished in 62% overall yield starting from commercially available (2S)-hydroxymethylaziridine via osmium-catalyzed asymmetric dihydroxylation as a key step.

Original languageEnglish
Pages (from-to)79-81
Number of pages3
JournalChemical Communications
Issue number1
DOIs
Publication statusPublished - 2007 Jan 1
Externally publishedYes

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ASJC Scopus subject areas

  • Chemistry(all)

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