Direct electrical measurement of protein-water interactions and temperature dependence using piezoelectric microcantilevers

Jeong Hoon Lee, Kyo Seon Hwang, Dae Sung Yoon, Ji Yoon Kang, Sang Kyung Kim, Tae Song Kim

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

A platform that provides a fundamental tool to understand protein behaviors by a simple real-time electrical readout is demonstrated. Observing the temperature dependence of protein activity as well as the humidity-sensitive protein activity of a prostate-specific antigen (PSA) monoclonal antibody receptor (MAbs), as well as PSA-MAbs receptor complexes, provides a stability curve for the protein and a humidity dependence of their activity.

Original languageEnglish
Pages (from-to)2920-2923
Number of pages4
JournalAdvanced Materials
Volume23
Issue number26
DOIs
Publication statusPublished - 2011 Jul 12
Externally publishedYes

ASJC Scopus subject areas

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering

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