Abstract
A platform that provides a fundamental tool to understand protein behaviors by a simple real-time electrical readout is demonstrated. Observing the temperature dependence of protein activity as well as the humidity-sensitive protein activity of a prostate-specific antigen (PSA) monoclonal antibody receptor (MAbs), as well as PSA-MAbs receptor complexes, provides a stability curve for the protein and a humidity dependence of their activity.
| Original language | English |
|---|---|
| Pages (from-to) | 2920-2923 |
| Number of pages | 4 |
| Journal | Advanced Materials |
| Volume | 23 |
| Issue number | 26 |
| DOIs | |
| Publication status | Published - 2011 Jul 12 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Materials Science(all)
- Mechanics of Materials
- Mechanical Engineering
Cite this
Direct electrical measurement of protein-water interactions and temperature dependence using piezoelectric microcantilevers. / Lee, Jeong Hoon; Hwang, Kyo Seon; Yoon, Dae Sung; Kang, Ji Yoon; Kim, Sang Kyung; Kim, Tae Song.
In: Advanced Materials, Vol. 23, No. 26, 12.07.2011, p. 2920-2923.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Direct electrical measurement of protein-water interactions and temperature dependence using piezoelectric microcantilevers
AU - Lee, Jeong Hoon
AU - Hwang, Kyo Seon
AU - Yoon, Dae Sung
AU - Kang, Ji Yoon
AU - Kim, Sang Kyung
AU - Kim, Tae Song
PY - 2011/7/12
Y1 - 2011/7/12
N2 - A platform that provides a fundamental tool to understand protein behaviors by a simple real-time electrical readout is demonstrated. Observing the temperature dependence of protein activity as well as the humidity-sensitive protein activity of a prostate-specific antigen (PSA) monoclonal antibody receptor (MAbs), as well as PSA-MAbs receptor complexes, provides a stability curve for the protein and a humidity dependence of their activity.
AB - A platform that provides a fundamental tool to understand protein behaviors by a simple real-time electrical readout is demonstrated. Observing the temperature dependence of protein activity as well as the humidity-sensitive protein activity of a prostate-specific antigen (PSA) monoclonal antibody receptor (MAbs), as well as PSA-MAbs receptor complexes, provides a stability curve for the protein and a humidity dependence of their activity.
UR - http://www.scopus.com/inward/record.url?scp=79960247070&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79960247070&partnerID=8YFLogxK
U2 - 10.1002/adma.201101037
DO - 10.1002/adma.201101037
M3 - Article
C2 - 21567485
AN - SCOPUS:79960247070
VL - 23
SP - 2920
EP - 2923
JO - Advanced Materials
JF - Advanced Materials
SN - 0935-9648
IS - 26
ER -