Direct electrical measurement of protein-water interactions and temperature dependence using piezoelectric microcantilevers

Jeong Hoon Lee, Kyo Seon Hwang, Dae Sung Yoon, Ji Yoon Kang, Sang Kyung Kim, Tae Song Kim

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

A platform that provides a fundamental tool to understand protein behaviors by a simple real-time electrical readout is demonstrated. Observing the temperature dependence of protein activity as well as the humidity-sensitive protein activity of a prostate-specific antigen (PSA) monoclonal antibody receptor (MAbs), as well as PSA-MAbs receptor complexes, provides a stability curve for the protein and a humidity dependence of their activity.

Original languageEnglish
Pages (from-to)2920-2923
Number of pages4
JournalAdvanced Materials
Volume23
Issue number26
DOIs
Publication statusPublished - 2011 Jul 12
Externally publishedYes

Fingerprint

Proteins
Water
Prostate-Specific Antigen
Antigens
Atmospheric humidity
Temperature
Monoclonal antibodies
Monoclonal Antibodies

ASJC Scopus subject areas

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering

Cite this

Direct electrical measurement of protein-water interactions and temperature dependence using piezoelectric microcantilevers. / Lee, Jeong Hoon; Hwang, Kyo Seon; Yoon, Dae Sung; Kang, Ji Yoon; Kim, Sang Kyung; Kim, Tae Song.

In: Advanced Materials, Vol. 23, No. 26, 12.07.2011, p. 2920-2923.

Research output: Contribution to journalArticle

Lee, Jeong Hoon ; Hwang, Kyo Seon ; Yoon, Dae Sung ; Kang, Ji Yoon ; Kim, Sang Kyung ; Kim, Tae Song. / Direct electrical measurement of protein-water interactions and temperature dependence using piezoelectric microcantilevers. In: Advanced Materials. 2011 ; Vol. 23, No. 26. pp. 2920-2923.
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