Disease spectrum of cervical lymphadenitis

Analysis based on ultrasound-guided core-needle gun biopsy

Joon-Young Song, Hee-Jin Cheong, Sae Yoon Kee, Jacob Lee, Jang Wook Sohn, Ja Kim Min, Sang I L Seo, In Sun Kim, Woo Joo Kim

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

Objectives: Despite the high frequency of cervical lymphadenopathy in the outpatient clinics, there was no published data on the disease spectrum of cervical lymphadenopathy among adult outpatients. We are evaluating the disease spectrum of cervical lymphadenitis in the outpatient setting. Methods: As for the patients with cervical lymphadenitis, ultrasound-guided core-needle gun biopsy has been performed in Korea University Hospital. We reviewed medical records of adult outpatients with cervical lymphadenitis between January 2004 and April 2006, and compared the clinical, laboratory and radiological differences among them. Results: The study included 147 patients with the mean age of 33.7 years. Histopathological diagnoses were obtained from 137 (93.2%) cases: Kikuchi's disease (34.7%), tuberculous lymphadenitis (22.4%), non-specific lymphadenitis (22.4%), lymphoma (6.1%), metastatic carcinoma (3.4%), etc. Overall, clinical manifestations were indistinguishable among tuberculous lymphadenitis, Kikuchi's disease and non-specific lymphadenitis. Leucopenia was characteristic of Kikuchi's disease, while anemia, thrombocytosis and pulmonary tuberculosis (irrespective of activity) were more common in the tuberculous lymphadenitis. Conclusion: Kikuchi's disease and tuberculosis were the most common and clinically important causes of cervical lymphadenitis. Complete blood count, chest X-ray and ultrasound-guided core-needle gun biopsy would be helpful in the differential diagnosis of cervical lymphadenitis, especially between Kikuchi's disease and tuberculous lymphadenitis.

Original languageEnglish
Pages (from-to)310-316
Number of pages7
JournalJournal of Infection
Volume55
Issue number4
DOIs
Publication statusPublished - 2007 Oct 1

Fingerprint

Large-Core Needle Biopsy
Lymphadenitis
Firearms
Histiocytic Necrotizing Lymphadenitis
Lymph Node Tuberculosis
Outpatients
Thrombocytosis
Blood Cell Count
Leukopenia
Korea
Ambulatory Care Facilities
Pulmonary Tuberculosis
Medical Records
Anemia
Lymphoma
Tuberculosis
Differential Diagnosis
Thorax
X-Rays
Carcinoma

Keywords

  • Cervical lymphadenitis
  • Core-needle gun biopsy
  • Pathology

ASJC Scopus subject areas

  • Applied Microbiology and Biotechnology
  • Microbiology
  • Parasitology
  • Virology
  • Immunology and Allergy
  • Infectious Diseases

Cite this

Disease spectrum of cervical lymphadenitis : Analysis based on ultrasound-guided core-needle gun biopsy. / Song, Joon-Young; Cheong, Hee-Jin; Kee, Sae Yoon; Lee, Jacob; Sohn, Jang Wook; Min, Ja Kim; Seo, Sang I L; Kim, In Sun; Kim, Woo Joo.

In: Journal of Infection, Vol. 55, No. 4, 01.10.2007, p. 310-316.

Research output: Contribution to journalArticle

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