Disseminated mycobacterium avium complex infection in an immunocompetent pregnant woman

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Abstract

Background: Disseminated mycobacterium avium complex (MAC) occurs mainly in immunocompromised hosts, which is associated with abnormal cellular immunity. Case presentation: A 26-year-old pregnant woman presented with fever and general weakness. Miliary lung nodules were noted on chest X-ray. Under the impression of miliary tuberculosis, anti-tuberculosis medication was administered. However, the patient was not improved. Further workup demonstrated MAC in the sputum and placenta. The patient was treated successfully with clarithromycin-based combination regimen. Conclusion: This appears to be the first case of disseminated MAC in an otherwise healthy pregnant woman. Clinicians should be alert for the diagnosis of MAC infection in diverse clinical conditions.

Original languageEnglish
Article number154
JournalBMC Infectious Diseases
Volume6
DOIs
Publication statusPublished - 2006 Oct 22

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Mycobacterium avium Complex
Pregnant Women
Infection
Miliary Tuberculosis
faropenem medoxomil
Clarithromycin
Immunocompromised Host
Sputum
Cellular Immunity
Placenta
Tuberculosis
Fever
Thorax
X-Rays
Lung

ASJC Scopus subject areas

  • Infectious Diseases

Cite this

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title = "Disseminated mycobacterium avium complex infection in an immunocompetent pregnant woman",
abstract = "Background: Disseminated mycobacterium avium complex (MAC) occurs mainly in immunocompromised hosts, which is associated with abnormal cellular immunity. Case presentation: A 26-year-old pregnant woman presented with fever and general weakness. Miliary lung nodules were noted on chest X-ray. Under the impression of miliary tuberculosis, anti-tuberculosis medication was administered. However, the patient was not improved. Further workup demonstrated MAC in the sputum and placenta. The patient was treated successfully with clarithromycin-based combination regimen. Conclusion: This appears to be the first case of disseminated MAC in an otherwise healthy pregnant woman. Clinicians should be alert for the diagnosis of MAC infection in diverse clinical conditions.",
author = "Joon-Young Song and Park, {Cheong Won} and Kee, {Sae Yoon} and Wonseok Choi and Eun-Young Kang and Sohn, {Jang Wook} and Kim, {Woo Joo} and Min, {Ja Kim} and Hee-Jin Cheong",
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AU - Song, Joon-Young

AU - Park, Cheong Won

AU - Kee, Sae Yoon

AU - Choi, Wonseok

AU - Kang, Eun-Young

AU - Sohn, Jang Wook

AU - Kim, Woo Joo

AU - Min, Ja Kim

AU - Cheong, Hee-Jin

PY - 2006/10/22

Y1 - 2006/10/22

N2 - Background: Disseminated mycobacterium avium complex (MAC) occurs mainly in immunocompromised hosts, which is associated with abnormal cellular immunity. Case presentation: A 26-year-old pregnant woman presented with fever and general weakness. Miliary lung nodules were noted on chest X-ray. Under the impression of miliary tuberculosis, anti-tuberculosis medication was administered. However, the patient was not improved. Further workup demonstrated MAC in the sputum and placenta. The patient was treated successfully with clarithromycin-based combination regimen. Conclusion: This appears to be the first case of disseminated MAC in an otherwise healthy pregnant woman. Clinicians should be alert for the diagnosis of MAC infection in diverse clinical conditions.

AB - Background: Disseminated mycobacterium avium complex (MAC) occurs mainly in immunocompromised hosts, which is associated with abnormal cellular immunity. Case presentation: A 26-year-old pregnant woman presented with fever and general weakness. Miliary lung nodules were noted on chest X-ray. Under the impression of miliary tuberculosis, anti-tuberculosis medication was administered. However, the patient was not improved. Further workup demonstrated MAC in the sputum and placenta. The patient was treated successfully with clarithromycin-based combination regimen. Conclusion: This appears to be the first case of disseminated MAC in an otherwise healthy pregnant woman. Clinicians should be alert for the diagnosis of MAC infection in diverse clinical conditions.

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