Distributions of antibody titers to Mycoplasma pneumoniae in Korean children in 2000-2003

Jinho Yu, Young Yoo, Kyun Kim Do, Hee Kang, Yull Koh Young

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    15 Citations (Scopus)

    Abstract

    The aim of study was to describe Mycoplasma pneumoniae epidemics in a hospital-based population. Special attention was paid to the relationship between antibody titer to M. pneumoniae and sex, age, and atopy. During the eight 6-month periods between January 2000 and December 2003, serum samples were obtained from 1,319 Korean children who presented with respiratory symptoms, and were examined for antibodies to M. pneumoniae using the indirect particle agglutination test. Geometric mean antibody titers peaked in the second half of 2000 and then decreased gradually, a second peak occurred in the second half of 2003. Likewise, the frequency of high antibody titers (≥ 1:640) also peaked during these two periods. Antibody titers in children aged 0-3 yr were lower than in older children during both peak periods and for 2 yr after the first peak. Sex and atopy had no effect on antibody titers. During the years 2000-2003, geometric mean antibody titers and the frequencies of high antibody titers varied with time. These changes suggest a cyclic pattern of M. pneumoniae infection, with two epidemic peaks separated by 3 yr.

    Original languageEnglish
    Pages (from-to)542-547
    Number of pages6
    JournalJournal of Korean medical science
    Volume20
    Issue number4
    DOIs
    Publication statusPublished - 2005 Aug

    Keywords

    • Age
    • Atopy
    • Child
    • Disease Outbreaks
    • Korea
    • Mycoplasma pneumoniae
    • Serologic Tests
    • Sex

    ASJC Scopus subject areas

    • Medicine(all)

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