Divergent ancestral lineages of newfound hantaviruses harbored by phylogenetically related crocidurine shrew species in Korea

Satoru Arai, Se Hun Gu, Luck Ju Baek, Kenji Tabara, Shannon N. Bennett, Hong Shik Oh, Nobuhiro Takada, Hae Ji Kang, Keiko Tanaka-Taya, Shigeru Morikawa, Nobuhiko Okabe, Richard Yanagihara, Jin Won Song

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42 Citations (Scopus)

Abstract

Spurred by the recent isolation of a novel hantavirus, named Imjin virus (MJNV), from the Ussuri white-toothed shrew (Crocidura lasiura), targeted trapping was conducted for the phylogenetically related Asian lesser white-toothed shrew (Crocidura shantungensis). Pair-wise alignment and comparison of the S, M and L segments of a newfound hantavirus, designated Jeju virus (JJUV), indicated remarkably low nucleotide and amino acid sequence similarity with MJNV. Phylogenetic analyses, using maximum likelihood and Bayesian methods, showed divergent ancestral lineages for JJUV and MJNV, despite the close phylogenetic relationship of their reservoir soricid hosts. Also, no evidence of host switching was apparent in tanglegrams, generated by TreeMap 2.0β.

Original languageEnglish
Pages (from-to)99-105
Number of pages7
JournalVirology
Volume424
Issue number2
DOIs
Publication statusPublished - 2012 Mar 15

Keywords

  • Crocidura
  • Hantavirus
  • Jeju Island
  • Korea
  • Phylogeny
  • Shrews

ASJC Scopus subject areas

  • Virology

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    Arai, S., Gu, S. H., Baek, L. J., Tabara, K., Bennett, S. N., Oh, H. S., Takada, N., Kang, H. J., Tanaka-Taya, K., Morikawa, S., Okabe, N., Yanagihara, R., & Song, J. W. (2012). Divergent ancestral lineages of newfound hantaviruses harbored by phylogenetically related crocidurine shrew species in Korea. Virology, 424(2), 99-105. https://doi.org/10.1016/j.virol.2011.11.013