Divergent lineage of a novel hantavirus in the banana pipistrelle (Neoromicia nanus) in Côte d'Ivoire

Laarni Sumibcay, Blaise Kadjo, Se Hun Gu, Hae Ji Kang, Burton K. Lim, Joseph A. Cook, Jin Won Song, Richard Yanagihara

Research output: Contribution to journalArticle

78 Citations (Scopus)

Abstract

Recently identified hantaviruses harbored by shrews and moles (order Soricomorpha) suggest that other mammals having shared ancestry may serve as reservoirs. To investigate this possibility, archival tissues from 213 insectivorous bats (order Chiroptera) were analyzed for hantavirus RNA by RT-PCR. Following numerous failed attempts, hantavirus RNA was detected in ethanol-fixed liver tissue from two banana pipistrelles (Neoromicia nanus), captured near Mouyassué village in Côte d'Ivoire, West Africa, in June 2011. Phylogenetic analysis of partial L-segment sequences using maximum-likelihood and Bayesian methods revealed that the newfound hantavirus, designated Mouyassué virus (MOUV), was highly divergent and basal to all other rodent- and soricomorph-borne hantaviruses, except for Nova virus in the European common mole (Talpa europaea). Full genome sequencing of MOUV and further surveys of other bat species for hantaviruses, now underway, will provide critical insights into the evolution and diversification of hantaviruses.

Original languageEnglish
Article number34
JournalVirology Journal
Volume9
DOIs
Publication statusPublished - 2012 Jan 27

Fingerprint

Hantavirus
Musa
Viruses
RNA
Shrews
Western Africa
Bayes Theorem
Mammals
Rodentia
Ethanol
Genome
Polymerase Chain Reaction
Liver

Keywords

  • Africa
  • Bat
  • Côte d'Ivoire
  • Hantavirus
  • Phylogeny

ASJC Scopus subject areas

  • Virology
  • Infectious Diseases

Cite this

Sumibcay, L., Kadjo, B., Gu, S. H., Kang, H. J., Lim, B. K., Cook, J. A., ... Yanagihara, R. (2012). Divergent lineage of a novel hantavirus in the banana pipistrelle (Neoromicia nanus) in Côte d'Ivoire. Virology Journal, 9, [34]. https://doi.org/10.1186/1743-422X-9-34

Divergent lineage of a novel hantavirus in the banana pipistrelle (Neoromicia nanus) in Côte d'Ivoire. / Sumibcay, Laarni; Kadjo, Blaise; Gu, Se Hun; Kang, Hae Ji; Lim, Burton K.; Cook, Joseph A.; Song, Jin Won; Yanagihara, Richard.

In: Virology Journal, Vol. 9, 34, 27.01.2012.

Research output: Contribution to journalArticle

Sumibcay, Laarni ; Kadjo, Blaise ; Gu, Se Hun ; Kang, Hae Ji ; Lim, Burton K. ; Cook, Joseph A. ; Song, Jin Won ; Yanagihara, Richard. / Divergent lineage of a novel hantavirus in the banana pipistrelle (Neoromicia nanus) in Côte d'Ivoire. In: Virology Journal. 2012 ; Vol. 9.
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