DIY 3D Microparticle Generation from Next Generation Optofluidic Fabrication

Kevin S. Paulsen, Yanxiang Deng, Aram Chung

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Complex-shaped microparticles can enhance applications in drug delivery, tissue engineering, and structural materials, although techniques to fabricate these particles remain limited. A microfluidics-based process called optofluidic fabrication that utilizes inertial flows and ultraviolet polymerization has shown great potential for creating highly 3D-shaped particles in a high-throughput manner, but the particle dimensions are mainly at the millimeter scale. Here, a next generation optofluidic fabrication process is presented that utilizes on-the-fly fabricated multiscale fluidic channels producing customized sub-100 µm 3D-shaped microparticles. This flexible design scheme offers a user-friendly platform for rapid prototyping of new 3D particle shapes, providing greater potential for creating impactful engineered microparticles.

Original languageEnglish
Article number1800252
JournalAdvanced Science
Volume5
Issue number7
DOIs
Publication statusPublished - 2018 Jul 1

Fingerprint

Microfluidics
microparticles
Tissue Engineering
Polymerization
Fabrication
fabrication
Fluidics
Rapid prototyping
Drug delivery
Tissue engineering
Pharmaceutical Preparations
Throughput
rapid prototyping
tissue engineering
fluidics
delivery
drugs
polymerization
platforms

Keywords

  • 3D microparticles
  • inertial microfluidics
  • optofluidic fabrication
  • optofluidics

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Chemical Engineering(all)
  • Materials Science(all)
  • Biochemistry, Genetics and Molecular Biology (miscellaneous)
  • Engineering(all)
  • Physics and Astronomy(all)

Cite this

DIY 3D Microparticle Generation from Next Generation Optofluidic Fabrication. / Paulsen, Kevin S.; Deng, Yanxiang; Chung, Aram.

In: Advanced Science, Vol. 5, No. 7, 1800252, 01.07.2018.

Research output: Contribution to journalArticle

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