Do baby brain cortices that look alike at birth grow alike during the first year of postnatal development?

Islem Rekik, Gang Li, Weili Lin, Dinggang Shen

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

The neonatal brain cortex is marked with complex and high-convoluted morphology, that undergoes dramatic changes over the first year of postnatal development. A large body of existing research works investigating ‘the developing brain’ have focused on looking at changes in cortical morphology and charting the developmental trajectories of the cortex. However, the relationship between neonatal cortical morphology and its postnatal growth trajectory was poorly investigated. Notably, understanding the multi-scale shape-growth relationship may help identify early neurodevelopmental disorders that affect it. Here, we unprecedentedly explore the question: “Do cortices that look alike in shape at birth have similar kinetic growth patterns?”. To this aim, we propose to analyze shape-growth relationship at three different scales. On a global scale, we found that neonatal cortices similar in geometric closeness are significantly correlated with their postnatal overall growth dynamics from birth till 1-year-old (r= 0.27). This finding was replicated when using shape similarity in morphology (r= 0.20). On a local scale, for both hemispheres, 20% of cortical regions displayed a significant high correlation (r> 0.4) between their similarities in morphology and dynamics. On a connectional scale, we identified hubs of cortical regions that were consistently similar in morphology and developed similarly across subjects including the cingulate cortex using a novel integral shape-growth brain graph representation.

Original languageEnglish
Title of host publicationMedical Image Computing and Computer Assisted Intervention – MICCAI 2018 - 21st International Conference, 2018, Proceedings
EditorsAlejandro F. Frangi, Christos Davatzikos, Gabor Fichtinger, Carlos Alberola-López, Julia A. Schnabel
PublisherSpringer Verlag
Pages566-574
Number of pages9
ISBN (Print)9783030009304
DOIs
Publication statusPublished - 2018 Jan 1
Externally publishedYes
Event21st International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2018 - Granada, Spain
Duration: 2018 Sep 162018 Sep 20

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume11072 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Other

Other21st International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2018
CountrySpain
CityGranada
Period18/9/1618/9/20

Fingerprint

Alike
Cortex
Brain
Trajectories
Trajectory
Graph Representation
Hemisphere
Growth kinetics
Disorder
Kinetics
Relationships

ASJC Scopus subject areas

  • Theoretical Computer Science
  • Computer Science(all)

Cite this

Rekik, I., Li, G., Lin, W., & Shen, D. (2018). Do baby brain cortices that look alike at birth grow alike during the first year of postnatal development? In A. F. Frangi, C. Davatzikos, G. Fichtinger, C. Alberola-López, & J. A. Schnabel (Eds.), Medical Image Computing and Computer Assisted Intervention – MICCAI 2018 - 21st International Conference, 2018, Proceedings (pp. 566-574). (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); Vol. 11072 LNCS). Springer Verlag. https://doi.org/10.1007/978-3-030-00931-1_65

Do baby brain cortices that look alike at birth grow alike during the first year of postnatal development? / Rekik, Islem; Li, Gang; Lin, Weili; Shen, Dinggang.

Medical Image Computing and Computer Assisted Intervention – MICCAI 2018 - 21st International Conference, 2018, Proceedings. ed. / Alejandro F. Frangi; Christos Davatzikos; Gabor Fichtinger; Carlos Alberola-López; Julia A. Schnabel. Springer Verlag, 2018. p. 566-574 (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); Vol. 11072 LNCS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Rekik, I, Li, G, Lin, W & Shen, D 2018, Do baby brain cortices that look alike at birth grow alike during the first year of postnatal development? in AF Frangi, C Davatzikos, G Fichtinger, C Alberola-López & JA Schnabel (eds), Medical Image Computing and Computer Assisted Intervention – MICCAI 2018 - 21st International Conference, 2018, Proceedings. Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), vol. 11072 LNCS, Springer Verlag, pp. 566-574, 21st International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2018, Granada, Spain, 18/9/16. https://doi.org/10.1007/978-3-030-00931-1_65
Rekik I, Li G, Lin W, Shen D. Do baby brain cortices that look alike at birth grow alike during the first year of postnatal development? In Frangi AF, Davatzikos C, Fichtinger G, Alberola-López C, Schnabel JA, editors, Medical Image Computing and Computer Assisted Intervention – MICCAI 2018 - 21st International Conference, 2018, Proceedings. Springer Verlag. 2018. p. 566-574. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)). https://doi.org/10.1007/978-3-030-00931-1_65
Rekik, Islem ; Li, Gang ; Lin, Weili ; Shen, Dinggang. / Do baby brain cortices that look alike at birth grow alike during the first year of postnatal development?. Medical Image Computing and Computer Assisted Intervention – MICCAI 2018 - 21st International Conference, 2018, Proceedings. editor / Alejandro F. Frangi ; Christos Davatzikos ; Gabor Fichtinger ; Carlos Alberola-López ; Julia A. Schnabel. Springer Verlag, 2018. pp. 566-574 (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)).
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