Do patients benefit from total intracorporeal robotic radical cystectomy? A comparative analysis with extracorporeal robotic radical cystectomy from a Korean multicenter study

Ji Sung Shim, Tae Gyun Kwon, Koon Ho Rha, Young Goo Lee, Ji Youl Lee, Byong Chang Jeong, Jong Hyun Pyun, Sung Gu Kang, Seok Ho Kang

Research output: Contribution to journalArticle

Abstract

Purpose: This study aimed to compare complications, perioperative parameters, and oncologic outcomes between robot-assisted radical cystectomy (RARC) with extracorporeal urinary diversion (ECUD) and RARC with intracorporeal urinary diversion (ICUD). Materials and Methods: Between 2007 and 2017, 362 patients who underwent RARC with ECUD or ICUD at multiple tertiary referral institutions were assessed. The primary endpoints were complication rates. The secondary outcomes were perioperative recovery parameters and oncological outcomes including estimated recurrence-free survival (RFS) and recurrence pattern between the 2 groups. Additionally, the complication rates of 2 expert surgeons with experience of >100 RARCs were analyzed. Results: The ICUD group showed lower overall, gastrointestinal, and genitourinary complications (p=0.001, p=0.036, and p=0.036, respectively) than the ECUD group. Concerning perioperative outcomes, the ICUD group had a significantly longer operation time (p=0.002), although recovery parameters such as time to flatus passage, oral intake, and length of hospital stay were significantly shorter in this group (p=0.001, p<0.001, and p<0.001, respectively). There was no difference in oncologic outcomes such as positive margin rate (p=0.944) and 2-year RFS (p=0.496), and in the recurrence pattern between groups. In the comparison of the expert surgeons’ complication rates, the major and total complication rates did not show differences (p=0.814 and p=0.102, respec-tively) while the minor complication rates were lower in the ICUD group (p=0.058). Conclusions: This multi-institutional cohort study demonstrated the benefits of the ICUD approach, as indicated by lower complication rates and better recovery parameters, although the oncological results were similar to those of ECUD.

Original languageEnglish
Pages (from-to)11-18
Number of pages8
JournalInvestigative and Clinical Urology
Volume61
Issue number1
DOIs
Publication statusPublished - 2020 Jan

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Urinary Diversion
Cystectomy
Robotics
Multicenter Studies
Recurrence
Length of Stay
Flatulence
Survival
Cohort Studies
Referral and Consultation

Keywords

  • Cystectomy
  • Recurrence
  • Robotics
  • Urinary bladder neoplasms
  • Urinary diversion

ASJC Scopus subject areas

  • Urology

Cite this

Do patients benefit from total intracorporeal robotic radical cystectomy? A comparative analysis with extracorporeal robotic radical cystectomy from a Korean multicenter study. / Shim, Ji Sung; Kwon, Tae Gyun; Rha, Koon Ho; Lee, Young Goo; Lee, Ji Youl; Jeong, Byong Chang; Pyun, Jong Hyun; Kang, Sung Gu; Kang, Seok Ho.

In: Investigative and Clinical Urology, Vol. 61, No. 1, 01.2020, p. 11-18.

Research output: Contribution to journalArticle

Shim, Ji Sung ; Kwon, Tae Gyun ; Rha, Koon Ho ; Lee, Young Goo ; Lee, Ji Youl ; Jeong, Byong Chang ; Pyun, Jong Hyun ; Kang, Sung Gu ; Kang, Seok Ho. / Do patients benefit from total intracorporeal robotic radical cystectomy? A comparative analysis with extracorporeal robotic radical cystectomy from a Korean multicenter study. In: Investigative and Clinical Urology. 2020 ; Vol. 61, No. 1. pp. 11-18.
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abstract = "Purpose: This study aimed to compare complications, perioperative parameters, and oncologic outcomes between robot-assisted radical cystectomy (RARC) with extracorporeal urinary diversion (ECUD) and RARC with intracorporeal urinary diversion (ICUD). Materials and Methods: Between 2007 and 2017, 362 patients who underwent RARC with ECUD or ICUD at multiple tertiary referral institutions were assessed. The primary endpoints were complication rates. The secondary outcomes were perioperative recovery parameters and oncological outcomes including estimated recurrence-free survival (RFS) and recurrence pattern between the 2 groups. Additionally, the complication rates of 2 expert surgeons with experience of >100 RARCs were analyzed. Results: The ICUD group showed lower overall, gastrointestinal, and genitourinary complications (p=0.001, p=0.036, and p=0.036, respectively) than the ECUD group. Concerning perioperative outcomes, the ICUD group had a significantly longer operation time (p=0.002), although recovery parameters such as time to flatus passage, oral intake, and length of hospital stay were significantly shorter in this group (p=0.001, p<0.001, and p<0.001, respectively). There was no difference in oncologic outcomes such as positive margin rate (p=0.944) and 2-year RFS (p=0.496), and in the recurrence pattern between groups. In the comparison of the expert surgeons’ complication rates, the major and total complication rates did not show differences (p=0.814 and p=0.102, respec-tively) while the minor complication rates were lower in the ICUD group (p=0.058). Conclusions: This multi-institutional cohort study demonstrated the benefits of the ICUD approach, as indicated by lower complication rates and better recovery parameters, although the oncological results were similar to those of ECUD.",
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T1 - Do patients benefit from total intracorporeal robotic radical cystectomy?

T2 - A comparative analysis with extracorporeal robotic radical cystectomy from a Korean multicenter study

AU - Shim, Ji Sung

AU - Kwon, Tae Gyun

AU - Rha, Koon Ho

AU - Lee, Young Goo

AU - Lee, Ji Youl

AU - Jeong, Byong Chang

AU - Pyun, Jong Hyun

AU - Kang, Sung Gu

AU - Kang, Seok Ho

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AB - Purpose: This study aimed to compare complications, perioperative parameters, and oncologic outcomes between robot-assisted radical cystectomy (RARC) with extracorporeal urinary diversion (ECUD) and RARC with intracorporeal urinary diversion (ICUD). Materials and Methods: Between 2007 and 2017, 362 patients who underwent RARC with ECUD or ICUD at multiple tertiary referral institutions were assessed. The primary endpoints were complication rates. The secondary outcomes were perioperative recovery parameters and oncological outcomes including estimated recurrence-free survival (RFS) and recurrence pattern between the 2 groups. Additionally, the complication rates of 2 expert surgeons with experience of >100 RARCs were analyzed. Results: The ICUD group showed lower overall, gastrointestinal, and genitourinary complications (p=0.001, p=0.036, and p=0.036, respectively) than the ECUD group. Concerning perioperative outcomes, the ICUD group had a significantly longer operation time (p=0.002), although recovery parameters such as time to flatus passage, oral intake, and length of hospital stay were significantly shorter in this group (p=0.001, p<0.001, and p<0.001, respectively). There was no difference in oncologic outcomes such as positive margin rate (p=0.944) and 2-year RFS (p=0.496), and in the recurrence pattern between groups. In the comparison of the expert surgeons’ complication rates, the major and total complication rates did not show differences (p=0.814 and p=0.102, respec-tively) while the minor complication rates were lower in the ICUD group (p=0.058). Conclusions: This multi-institutional cohort study demonstrated the benefits of the ICUD approach, as indicated by lower complication rates and better recovery parameters, although the oncological results were similar to those of ECUD.

KW - Cystectomy

KW - Recurrence

KW - Robotics

KW - Urinary bladder neoplasms

KW - Urinary diversion

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