Droplet-based magnetically activated cell separator (DMACS): Evaluation of separation efficiency versus variance of magnetic flux density

Youngho Kim, Su Hong, Sang Ho Lee, Kyeongkap Paek, Byungkyu Kim

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

We introduced a droplet-based magnetically activated cell separator (DMACS) that utilizes a hanging droplet of microliter-sized volume for dividing positive (magnetically labeled) and negative (magnetically unlabeled) cells. It enabled us to solve adhesion problem in channel and showed better separation efficiency. However, the separation efficiency was changed under variations of initial volume (the droplet volume of cell suspension before buffer injection process for dividing the hanging droplet into two fractions). Therefore, the efficiencies corresponding to initial volumes were investigated in experimental study. We found that the initial volume should be optimized to find maximum separation efficiency.

Original languageEnglish
Title of host publicationProceedings of IEEE Sensors
Pages162-165
Number of pages4
DOIs
Publication statusPublished - 2006 Dec 1
Event2006 5th IEEE Conference on Sensors - Daegu, Korea, Republic of
Duration: 2006 Oct 222006 Oct 25

Other

Other2006 5th IEEE Conference on Sensors
CountryKorea, Republic of
CityDaegu
Period06/10/2206/10/25

ASJC Scopus subject areas

  • Engineering (miscellaneous)
  • Electrical and Electronic Engineering

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