Abstract
In all clinical trials comparing rate versus rhythm control of atrial fibrillation (AF) by drugs, there was no survival benefit associated with a rhythm control strategy. Currently used antiarrhythmic drugs are not only frequently ineffective at eliminating AF, but may be life threatening In some patients. Catheter ablation (CA) of AF has evolved rapidly and has become accepted as one of the therapeutic modalities for controlling AF. The effective strategies for CA of AF consist of pulmonary vein isolation (PVI) and/or complete encirclement around PVs with or without additional ablation lines. Selection of patients, who may be benefited by CA or not, Is an important Issue. Precise electroanatomic mapping for the triggers and the substrate of the atria is central for customizing ablation target and for enhancing efficacy of CA for AF. With further development of new energy sources of ablation, cardiac imaging, navigation, and mapping systems, the CA can be simplified and standardized, which may enable the CA to become more effective, safer, and more applicable to many different subsets of AF.
| Original language | English |
|---|---|
| Pages (from-to) | 317-326 |
| Number of pages | 10 |
| Journal | Journal of the Korean Medical Association |
| Volume | 51 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - 2008 Apr 1 |
Fingerprint
Keywords
- Antiarrhythmic drugs
- Atrial fibrillation
- Catheter ablation
- Mapping
ASJC Scopus subject areas
- Medicine(all)
Cite this
Drug therapy and catheter ablation for atrill fibrillation. / Kim, Young Hoon.
In: Journal of the Korean Medical Association, Vol. 51, No. 4, 01.04.2008, p. 317-326.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Drug therapy and catheter ablation for atrill fibrillation
AU - Kim, Young Hoon
PY - 2008/4/1
Y1 - 2008/4/1
N2 - In all clinical trials comparing rate versus rhythm control of atrial fibrillation (AF) by drugs, there was no survival benefit associated with a rhythm control strategy. Currently used antiarrhythmic drugs are not only frequently ineffective at eliminating AF, but may be life threatening In some patients. Catheter ablation (CA) of AF has evolved rapidly and has become accepted as one of the therapeutic modalities for controlling AF. The effective strategies for CA of AF consist of pulmonary vein isolation (PVI) and/or complete encirclement around PVs with or without additional ablation lines. Selection of patients, who may be benefited by CA or not, Is an important Issue. Precise electroanatomic mapping for the triggers and the substrate of the atria is central for customizing ablation target and for enhancing efficacy of CA for AF. With further development of new energy sources of ablation, cardiac imaging, navigation, and mapping systems, the CA can be simplified and standardized, which may enable the CA to become more effective, safer, and more applicable to many different subsets of AF.
AB - In all clinical trials comparing rate versus rhythm control of atrial fibrillation (AF) by drugs, there was no survival benefit associated with a rhythm control strategy. Currently used antiarrhythmic drugs are not only frequently ineffective at eliminating AF, but may be life threatening In some patients. Catheter ablation (CA) of AF has evolved rapidly and has become accepted as one of the therapeutic modalities for controlling AF. The effective strategies for CA of AF consist of pulmonary vein isolation (PVI) and/or complete encirclement around PVs with or without additional ablation lines. Selection of patients, who may be benefited by CA or not, Is an important Issue. Precise electroanatomic mapping for the triggers and the substrate of the atria is central for customizing ablation target and for enhancing efficacy of CA for AF. With further development of new energy sources of ablation, cardiac imaging, navigation, and mapping systems, the CA can be simplified and standardized, which may enable the CA to become more effective, safer, and more applicable to many different subsets of AF.
KW - Antiarrhythmic drugs
KW - Atrial fibrillation
KW - Catheter ablation
KW - Mapping
UR - http://www.scopus.com/inward/record.url?scp=78549244101&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=78549244101&partnerID=8YFLogxK
U2 - 10.5124/jkma.2008.51.4.317
DO - 10.5124/jkma.2008.51.4.317
M3 - Article
VL - 51
SP - 317
EP - 326
JO - Journal of the Korean Medical Association
JF - Journal of the Korean Medical Association
SN - 1975-8456
IS - 4
ER -