Abstract
We report two-photon probes (FMg1 and FMg2) that can selectively detect intracellular free Mg2+ ([Mg2+]i) in live cells and tissues by two-photon microscopy. Combined with BCaM, a two-photon probe for near-membrane Ca2+ ([Ca2+]m), FMg2 allows dual-color imaging of Mg2+/Ca2+ activities in live cells and [Mg2+]i /[Ca2+]m distributions in live tissues at a depth of 100-200 μm.
Original language | English |
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Pages (from-to) | 8110-8113 |
Number of pages | 4 |
Journal | Analytical chemistry |
Volume | 84 |
Issue number | 19 |
DOIs | |
Publication status | Published - 2012 Oct 2 |
ASJC Scopus subject areas
- Analytical Chemistry