Abstract
We studied the dynamical response of a nanomechanical resonator to biomolecular (e.g., DNA) adsorptions on a resonator's surface by using theoretical model, which considers the Hamiltonian H such that the potential energy consists of elastic bending energy of a resonator and the potential energy for biomolecular interactions. It was shown that the resonant frequency shift for a resonator due to biomolecular adsorption depends on not only the mass of adsorbed biomolecules but also the biomolecular interactions. Specifically, for double-stranded DNA adsorption on a resonator's surface, the resonant frequency shift is also dependent on the ionic strength of a solvent, implying the role of biomolecular interactions on the dynamic behavior of a resonator. This indicates that nanomechanical resonators may enable one to quantify the biomolecular mass, implying the enumeration of biomolecules, as well as gain insight into intermolecular interactions between adsorbed biomolecules on the surface.
| Original language | English |
|---|---|
| Article number | 113408 |
| Journal | Physical Review B - Condensed Matter and Materials Physics |
| Volume | 76 |
| Issue number | 11 |
| DOIs | |
| Publication status | Published - 2007 Sep 19 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Condensed Matter Physics
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Dynamical response of nanomechanical resonators to biomolecular interactions. / Eom, Kilho; Kwon, Tae Yun; Yoon, Dae Sung; Lee, Hong Lim; Kim, Tae Song.
In: Physical Review B - Condensed Matter and Materials Physics, Vol. 76, No. 11, 113408, 19.09.2007.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Dynamical response of nanomechanical resonators to biomolecular interactions
AU - Eom, Kilho
AU - Kwon, Tae Yun
AU - Yoon, Dae Sung
AU - Lee, Hong Lim
AU - Kim, Tae Song
PY - 2007/9/19
Y1 - 2007/9/19
N2 - We studied the dynamical response of a nanomechanical resonator to biomolecular (e.g., DNA) adsorptions on a resonator's surface by using theoretical model, which considers the Hamiltonian H such that the potential energy consists of elastic bending energy of a resonator and the potential energy for biomolecular interactions. It was shown that the resonant frequency shift for a resonator due to biomolecular adsorption depends on not only the mass of adsorbed biomolecules but also the biomolecular interactions. Specifically, for double-stranded DNA adsorption on a resonator's surface, the resonant frequency shift is also dependent on the ionic strength of a solvent, implying the role of biomolecular interactions on the dynamic behavior of a resonator. This indicates that nanomechanical resonators may enable one to quantify the biomolecular mass, implying the enumeration of biomolecules, as well as gain insight into intermolecular interactions between adsorbed biomolecules on the surface.
AB - We studied the dynamical response of a nanomechanical resonator to biomolecular (e.g., DNA) adsorptions on a resonator's surface by using theoretical model, which considers the Hamiltonian H such that the potential energy consists of elastic bending energy of a resonator and the potential energy for biomolecular interactions. It was shown that the resonant frequency shift for a resonator due to biomolecular adsorption depends on not only the mass of adsorbed biomolecules but also the biomolecular interactions. Specifically, for double-stranded DNA adsorption on a resonator's surface, the resonant frequency shift is also dependent on the ionic strength of a solvent, implying the role of biomolecular interactions on the dynamic behavior of a resonator. This indicates that nanomechanical resonators may enable one to quantify the biomolecular mass, implying the enumeration of biomolecules, as well as gain insight into intermolecular interactions between adsorbed biomolecules on the surface.
UR - http://www.scopus.com/inward/record.url?scp=34648831893&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=34648831893&partnerID=8YFLogxK
U2 - 10.1103/PhysRevB.76.113408
DO - 10.1103/PhysRevB.76.113408
M3 - Article
VL - 76
JO - Physical Review B-Condensed Matter
JF - Physical Review B-Condensed Matter
SN - 1098-0121
IS - 11
M1 - 113408
ER -