Dynamical response of nanomechanical resonators to biomolecular interactions

Kilho Eom, Tae Yun Kwon, Dae Sung Yoon, Hong Lim Lee, Tae Song Kim

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

We studied the dynamical response of a nanomechanical resonator to biomolecular (e.g., DNA) adsorptions on a resonator's surface by using theoretical model, which considers the Hamiltonian H such that the potential energy consists of elastic bending energy of a resonator and the potential energy for biomolecular interactions. It was shown that the resonant frequency shift for a resonator due to biomolecular adsorption depends on not only the mass of adsorbed biomolecules but also the biomolecular interactions. Specifically, for double-stranded DNA adsorption on a resonator's surface, the resonant frequency shift is also dependent on the ionic strength of a solvent, implying the role of biomolecular interactions on the dynamic behavior of a resonator. This indicates that nanomechanical resonators may enable one to quantify the biomolecular mass, implying the enumeration of biomolecules, as well as gain insight into intermolecular interactions between adsorbed biomolecules on the surface.

Original languageEnglish
Article number113408
JournalPhysical Review B - Condensed Matter and Materials Physics
Volume76
Issue number11
DOIs
Publication statusPublished - 2007 Sep 19
Externally publishedYes

Fingerprint

Resonators
resonators
Biomolecules
interactions
Potential energy
Adsorption
frequency shift
adsorption
resonant frequencies
Natural frequencies
DNA
deoxyribonucleic acid
potential energy
elastic bending
Hamiltonians
enumeration
Ionic strength

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics

Cite this

Dynamical response of nanomechanical resonators to biomolecular interactions. / Eom, Kilho; Kwon, Tae Yun; Yoon, Dae Sung; Lee, Hong Lim; Kim, Tae Song.

In: Physical Review B - Condensed Matter and Materials Physics, Vol. 76, No. 11, 113408, 19.09.2007.

Research output: Contribution to journalArticle

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