Early assessment of myocardial contractility by contrast-enhanced magnetic resonance (ceMRI) imaging after revascularization in acute myocardial infarction (AMI)

Hong Euy Lim, Hwan-Seok Yong, Sung Hee Shin, Jeong Cheon Ahn, Hong Seog Seo, Dong Joo Oh, Young Moo Ro, Chang Gyu Park

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2 Citations (Scopus)

Abstract

Backgroud: Recent studies have demonstrated that the size and shape of the hyperenhanced areas on contrast-enhanced magnetic resonance imaging (ceMRI) were nearly identical to areas of irreversible injury, as defined by histochemical staining. We compared the transmural extent of infarct (TEI), as defined by ceMRI, to the initial ECG findings for acute myocardial infarction (AMI), and we also assessed functional contractility according to TEI. Methods: 12 patients who presented with their first myocardial infarction underwent cine and ceMRI 4 weeks later after their successful revascularization. TEI and wall thickening were determined by using a 30-segment model. Results: Infarction was observed in 81 (23.9%) segments, of which 46 segments (56.8%) had abnormal wall motion and 35 segments (43.2%) had normal wall motion. Of the 35 segments, 33 (94.3%) had subendocardial infarction. 17 segments had infarct of less than 25% of the wall thickness, and all of them had normal wall motion. On the other hand, 11 segments had infarct of more than 75% of wall thickness, of which 11 (100%) had abnormal wall motion. None of segments with nearly transmural infarction were observed in non ST-elevation AMI. The majority of the segments with infarct had non-transmural infarction (87.5%), even if the segments were in ST-elevation AMI (76.1%). Infarct size, as defined by ceMRI, was strongly correlated with peak CK-MB and Troponin-T (r=0.96, p<0.001, r=0.91, p<0.001, respectively). Conclusion: TEI defined by ceMRI is inversely related to the contractility after revascularization in AMI. We were able to predict the future contractile function of segments with infarction using ceMRI before revascularization.

Original languageEnglish
Pages (from-to)213-219
Number of pages7
JournalKorean Journal of Internal Medicine
Volume19
Issue number4
DOIs
Publication statusPublished - 2004 Jan 1

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Magnetic Resonance Spectroscopy
Infarction
Myocardial Infarction
Magnetic Resonance Imaging
Troponin T
Electrocardiography
Staining and Labeling
Wounds and Injuries

Keywords

  • Acute myocardial infarction (AMI)
  • Contractility
  • Contrast-enhanced magnetic resonance imaging (ceMRI)
  • Revascularization

ASJC Scopus subject areas

  • Internal Medicine

Cite this

@article{a8256483e31e42aeb302d100b6aadd5c,
title = "Early assessment of myocardial contractility by contrast-enhanced magnetic resonance (ceMRI) imaging after revascularization in acute myocardial infarction (AMI)",
abstract = "Backgroud: Recent studies have demonstrated that the size and shape of the hyperenhanced areas on contrast-enhanced magnetic resonance imaging (ceMRI) were nearly identical to areas of irreversible injury, as defined by histochemical staining. We compared the transmural extent of infarct (TEI), as defined by ceMRI, to the initial ECG findings for acute myocardial infarction (AMI), and we also assessed functional contractility according to TEI. Methods: 12 patients who presented with their first myocardial infarction underwent cine and ceMRI 4 weeks later after their successful revascularization. TEI and wall thickening were determined by using a 30-segment model. Results: Infarction was observed in 81 (23.9{\%}) segments, of which 46 segments (56.8{\%}) had abnormal wall motion and 35 segments (43.2{\%}) had normal wall motion. Of the 35 segments, 33 (94.3{\%}) had subendocardial infarction. 17 segments had infarct of less than 25{\%} of the wall thickness, and all of them had normal wall motion. On the other hand, 11 segments had infarct of more than 75{\%} of wall thickness, of which 11 (100{\%}) had abnormal wall motion. None of segments with nearly transmural infarction were observed in non ST-elevation AMI. The majority of the segments with infarct had non-transmural infarction (87.5{\%}), even if the segments were in ST-elevation AMI (76.1{\%}). Infarct size, as defined by ceMRI, was strongly correlated with peak CK-MB and Troponin-T (r=0.96, p<0.001, r=0.91, p<0.001, respectively). Conclusion: TEI defined by ceMRI is inversely related to the contractility after revascularization in AMI. We were able to predict the future contractile function of segments with infarction using ceMRI before revascularization.",
keywords = "Acute myocardial infarction (AMI), Contractility, Contrast-enhanced magnetic resonance imaging (ceMRI), Revascularization",
author = "Lim, {Hong Euy} and Hwan-Seok Yong and Shin, {Sung Hee} and Ahn, {Jeong Cheon} and Seo, {Hong Seog} and Oh, {Dong Joo} and Ro, {Young Moo} and Park, {Chang Gyu}",
year = "2004",
month = "1",
day = "1",
doi = "10.3904/kjim.2004.19.4.213",
language = "English",
volume = "19",
pages = "213--219",
journal = "Korean Journal of Internal Medicine",
issn = "0494-4712",
publisher = "Korean Association of Internal Medicine",
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TY - JOUR

T1 - Early assessment of myocardial contractility by contrast-enhanced magnetic resonance (ceMRI) imaging after revascularization in acute myocardial infarction (AMI)

AU - Lim, Hong Euy

AU - Yong, Hwan-Seok

AU - Shin, Sung Hee

AU - Ahn, Jeong Cheon

AU - Seo, Hong Seog

AU - Oh, Dong Joo

AU - Ro, Young Moo

AU - Park, Chang Gyu

PY - 2004/1/1

Y1 - 2004/1/1

N2 - Backgroud: Recent studies have demonstrated that the size and shape of the hyperenhanced areas on contrast-enhanced magnetic resonance imaging (ceMRI) were nearly identical to areas of irreversible injury, as defined by histochemical staining. We compared the transmural extent of infarct (TEI), as defined by ceMRI, to the initial ECG findings for acute myocardial infarction (AMI), and we also assessed functional contractility according to TEI. Methods: 12 patients who presented with their first myocardial infarction underwent cine and ceMRI 4 weeks later after their successful revascularization. TEI and wall thickening were determined by using a 30-segment model. Results: Infarction was observed in 81 (23.9%) segments, of which 46 segments (56.8%) had abnormal wall motion and 35 segments (43.2%) had normal wall motion. Of the 35 segments, 33 (94.3%) had subendocardial infarction. 17 segments had infarct of less than 25% of the wall thickness, and all of them had normal wall motion. On the other hand, 11 segments had infarct of more than 75% of wall thickness, of which 11 (100%) had abnormal wall motion. None of segments with nearly transmural infarction were observed in non ST-elevation AMI. The majority of the segments with infarct had non-transmural infarction (87.5%), even if the segments were in ST-elevation AMI (76.1%). Infarct size, as defined by ceMRI, was strongly correlated with peak CK-MB and Troponin-T (r=0.96, p<0.001, r=0.91, p<0.001, respectively). Conclusion: TEI defined by ceMRI is inversely related to the contractility after revascularization in AMI. We were able to predict the future contractile function of segments with infarction using ceMRI before revascularization.

AB - Backgroud: Recent studies have demonstrated that the size and shape of the hyperenhanced areas on contrast-enhanced magnetic resonance imaging (ceMRI) were nearly identical to areas of irreversible injury, as defined by histochemical staining. We compared the transmural extent of infarct (TEI), as defined by ceMRI, to the initial ECG findings for acute myocardial infarction (AMI), and we also assessed functional contractility according to TEI. Methods: 12 patients who presented with their first myocardial infarction underwent cine and ceMRI 4 weeks later after their successful revascularization. TEI and wall thickening were determined by using a 30-segment model. Results: Infarction was observed in 81 (23.9%) segments, of which 46 segments (56.8%) had abnormal wall motion and 35 segments (43.2%) had normal wall motion. Of the 35 segments, 33 (94.3%) had subendocardial infarction. 17 segments had infarct of less than 25% of the wall thickness, and all of them had normal wall motion. On the other hand, 11 segments had infarct of more than 75% of wall thickness, of which 11 (100%) had abnormal wall motion. None of segments with nearly transmural infarction were observed in non ST-elevation AMI. The majority of the segments with infarct had non-transmural infarction (87.5%), even if the segments were in ST-elevation AMI (76.1%). Infarct size, as defined by ceMRI, was strongly correlated with peak CK-MB and Troponin-T (r=0.96, p<0.001, r=0.91, p<0.001, respectively). Conclusion: TEI defined by ceMRI is inversely related to the contractility after revascularization in AMI. We were able to predict the future contractile function of segments with infarction using ceMRI before revascularization.

KW - Acute myocardial infarction (AMI)

KW - Contractility

KW - Contrast-enhanced magnetic resonance imaging (ceMRI)

KW - Revascularization

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