Abstract
The efficacy of local anaesthetic infiltration and/or non-steroidal anti-inflammatory drugs for post-operative analgesia following laparoscopic-assisted vaginal hysterectomy (LAVH) was investigated in 83 patients, randomized into four groups in this double-blind, placebo-controlled study: group BK, local infiltration with bupivacaine and pre-incisional intra-muscular (IM) ketorolac; group NN, saline local infiltration IM; group BN, local infiltration with bupivacaine and saline IM; group NK, local infiltration with saline and ketorolac IM. Post-operative pain scores were assessed at 1 h, 3 h, 6 h, 12 h and 24 h using a visual analogue scale (VAS). The major pain site, first analgesic request time and incidence of analgesic requests were also recorded. At 1 h, 3 h and 6 h after surgery, group BK patients had significantly lower VAS pain scores than group NN patients. The first analgesic request time was significantly longer in group BK than in groups NN, BN and NK. Pre-incisional treatment with ketorolac IM and local infiltration with bupivacaine reduced post-operative pain after LAVH.
| Original language | English |
|---|---|
| Pages (from-to) | 372-378 |
| Number of pages | 7 |
| Journal | Journal of International Medical Research |
| Volume | 33 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - 2005 Jan 1 |
Fingerprint
Keywords
- Bupivacaine
- Ketorolac
- Laparoscopic-assisted vaginal hysterectomy
- Post-operative pain
ASJC Scopus subject areas
- Biochemistry
- Cell Biology
- Biochemistry, medical
Cite this
Effect of administration of ketorolac and local anaesthetic infiltration for pain relief after laparoscopic-assisted vaginal hysterectomy. / Kim, Jae Hwan; Lee, Yoon Sook; Shin, Hye Won; Chang, M. S.; Park, Young Cheol; Kim, Woon Young.
In: Journal of International Medical Research, Vol. 33, No. 4, 01.01.2005, p. 372-378.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Effect of administration of ketorolac and local anaesthetic infiltration for pain relief after laparoscopic-assisted vaginal hysterectomy
AU - Kim, Jae Hwan
AU - Lee, Yoon Sook
AU - Shin, Hye Won
AU - Chang, M. S.
AU - Park, Young Cheol
AU - Kim, Woon Young
PY - 2005/1/1
Y1 - 2005/1/1
N2 - The efficacy of local anaesthetic infiltration and/or non-steroidal anti-inflammatory drugs for post-operative analgesia following laparoscopic-assisted vaginal hysterectomy (LAVH) was investigated in 83 patients, randomized into four groups in this double-blind, placebo-controlled study: group BK, local infiltration with bupivacaine and pre-incisional intra-muscular (IM) ketorolac; group NN, saline local infiltration IM; group BN, local infiltration with bupivacaine and saline IM; group NK, local infiltration with saline and ketorolac IM. Post-operative pain scores were assessed at 1 h, 3 h, 6 h, 12 h and 24 h using a visual analogue scale (VAS). The major pain site, first analgesic request time and incidence of analgesic requests were also recorded. At 1 h, 3 h and 6 h after surgery, group BK patients had significantly lower VAS pain scores than group NN patients. The first analgesic request time was significantly longer in group BK than in groups NN, BN and NK. Pre-incisional treatment with ketorolac IM and local infiltration with bupivacaine reduced post-operative pain after LAVH.
AB - The efficacy of local anaesthetic infiltration and/or non-steroidal anti-inflammatory drugs for post-operative analgesia following laparoscopic-assisted vaginal hysterectomy (LAVH) was investigated in 83 patients, randomized into four groups in this double-blind, placebo-controlled study: group BK, local infiltration with bupivacaine and pre-incisional intra-muscular (IM) ketorolac; group NN, saline local infiltration IM; group BN, local infiltration with bupivacaine and saline IM; group NK, local infiltration with saline and ketorolac IM. Post-operative pain scores were assessed at 1 h, 3 h, 6 h, 12 h and 24 h using a visual analogue scale (VAS). The major pain site, first analgesic request time and incidence of analgesic requests were also recorded. At 1 h, 3 h and 6 h after surgery, group BK patients had significantly lower VAS pain scores than group NN patients. The first analgesic request time was significantly longer in group BK than in groups NN, BN and NK. Pre-incisional treatment with ketorolac IM and local infiltration with bupivacaine reduced post-operative pain after LAVH.
KW - Bupivacaine
KW - Ketorolac
KW - Laparoscopic-assisted vaginal hysterectomy
KW - Post-operative pain
UR - http://www.scopus.com/inward/record.url?scp=23044477461&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=23044477461&partnerID=8YFLogxK
U2 - 10.1177/147323000503300402
DO - 10.1177/147323000503300402
M3 - Article
C2 - 16104440
AN - SCOPUS:23044477461
VL - 33
SP - 372
EP - 378
JO - Journal of International Medical Research
JF - Journal of International Medical Research
SN - 0300-0605
IS - 4
ER -