Effect of bowel preparation with polyethylene glycol on quality of capsule endoscopy

Sung Chul Park, Bora Keum, Yeon Seok Seo, Yong Sik Kim, Yoon Tae Jeen, Hoon Jai Chun, Soon Ho Um, Chang Duck Kim, Ho Sang Ryu

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42 Citations (Scopus)


Background and Aims: Capsule endoscopy (CE) has the problem that lumen visualization is impaired by bubbles, bile, and debris. The benefits of bowel preparation are still controversial and the best method remains to be determined. The objective of this study was to evaluate the effect of the method of bowel preparation on the quality of visualization and on transit time. Methods: The study sample consisted of 68 patients for CE. Patients were randomly allocated to three groups. In group A (n = 23), patients fasted for 12 h before CE. In groups B (n = 20) and C (n = 25), patients received 2 and 4 l of polyethylene glycol (PEG), respectively. Small bowel images were evaluated by use of a cleansing score system. Representative frames were serially selected at 5-min intervals and scored by assessment of two properties (proportion of luminal visibility and extent of obscuration). Results: The median scores of image quality in groups A, B, and C were 2.26, 2.43, and 2.55 respectively, (P = 0.034). Cecal completion rates, gastric transit time, and small bowel transit time were no different among the three groups. Detection of lesions in groups A, B, and C was 56.5, 65.0, and 68.0%, respectively. Conclusions: Bowel preparation with PEG resulted in better image quality than fasting alone. No significant difference was observed between 2 and 4 l. PEG 2 l rather than 4 l may be a useful method of preparation for CE.

Original languageEnglish
Pages (from-to)1769-1775
Number of pages7
JournalDigestive Diseases and Sciences
Issue number6
Publication statusPublished - 2011 Jun


  • Bowel preparation
  • Capsule endoscopy
  • Cleansing score system

ASJC Scopus subject areas

  • Physiology
  • Gastroenterology

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    Park, S. C., Keum, B., Seo, Y. S., Kim, Y. S., Jeen, Y. T., Chun, H. J., Um, S. H., Kim, C. D., & Ryu, H. S. (2011). Effect of bowel preparation with polyethylene glycol on quality of capsule endoscopy. Digestive Diseases and Sciences, 56(6), 1769-1775. https://doi.org/10.1007/s10620-010-1500-2