Effect of chelators and reductants on the mobilization of metals from ambient particulate matter

Hee Sang Song, Won Gi Bang, Namhyun Chung, Yong Sung Cho, Yoon Shin Kim, Myung Haing Cho

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Ambient urban particulate matter (PM) contains various transition metals. When the PM is inhaled into the lung, not all but some part of metals from the particles might be mobilized to participate in a reaction that can damage various biomolecules, such as DNA and proteins. The dust particle size as well as organic acids may influence the metal mobilization. Thus, the mobilization of the metal from two standard reference materials (SRM; NIST, USA) and urban PM (PM2.5 and PM10) collected in the Seoul area was measured in the presence of artificial or biological chelator with or without reductant. The degree of the mobilization was higher with the artificial or biological chelator than the control with saline. In some cases, a reductant increased the mobilization as much as about 5 times the control without the reductant. Especially, the mobilization of Fe was greatly influenced by the presence of reductants. In general, the degree of the mobilization of the transition metal was higher with PM2.5 than with PM10. Therefore, it is expected that, considering the previously known toxicities of the transition metals, PM2.5 is more damaging to various biomolecules than PM10. The results also suggest that not the total amount but the mobilizable fraction of the metal in the ambient PM should be considered with regard to the toxicity of the urban particulate matter.

Original languageEnglish
Pages (from-to)3531-3536
Number of pages6
JournalEnvironmental Science and Technology
Volume37
Issue number16
DOIs
Publication statusPublished - 2003 Aug 15

Fingerprint

Particulate Matter
Reducing Agents
Chelating Agents
mobilization
particulate matter
Metals
Transition metals
metal
transition element
Biomolecules
Toxicity
Organic acids
toxicity
Dust
DNA
Particle size
Proteins
organic acid
effect
Particle Size

ASJC Scopus subject areas

  • Environmental Engineering
  • Environmental Science(all)
  • Environmental Chemistry

Cite this

Effect of chelators and reductants on the mobilization of metals from ambient particulate matter. / Song, Hee Sang; Bang, Won Gi; Chung, Namhyun; Cho, Yong Sung; Kim, Yoon Shin; Cho, Myung Haing.

In: Environmental Science and Technology, Vol. 37, No. 16, 15.08.2003, p. 3531-3536.

Research output: Contribution to journalArticle

Song, Hee Sang ; Bang, Won Gi ; Chung, Namhyun ; Cho, Yong Sung ; Kim, Yoon Shin ; Cho, Myung Haing. / Effect of chelators and reductants on the mobilization of metals from ambient particulate matter. In: Environmental Science and Technology. 2003 ; Vol. 37, No. 16. pp. 3531-3536.
@article{2b187dbe10d242e78e9b677ebd4c1658,
title = "Effect of chelators and reductants on the mobilization of metals from ambient particulate matter",
abstract = "Ambient urban particulate matter (PM) contains various transition metals. When the PM is inhaled into the lung, not all but some part of metals from the particles might be mobilized to participate in a reaction that can damage various biomolecules, such as DNA and proteins. The dust particle size as well as organic acids may influence the metal mobilization. Thus, the mobilization of the metal from two standard reference materials (SRM; NIST, USA) and urban PM (PM2.5 and PM10) collected in the Seoul area was measured in the presence of artificial or biological chelator with or without reductant. The degree of the mobilization was higher with the artificial or biological chelator than the control with saline. In some cases, a reductant increased the mobilization as much as about 5 times the control without the reductant. Especially, the mobilization of Fe was greatly influenced by the presence of reductants. In general, the degree of the mobilization of the transition metal was higher with PM2.5 than with PM10. Therefore, it is expected that, considering the previously known toxicities of the transition metals, PM2.5 is more damaging to various biomolecules than PM10. The results also suggest that not the total amount but the mobilizable fraction of the metal in the ambient PM should be considered with regard to the toxicity of the urban particulate matter.",
author = "Song, {Hee Sang} and Bang, {Won Gi} and Namhyun Chung and Cho, {Yong Sung} and Kim, {Yoon Shin} and Cho, {Myung Haing}",
year = "2003",
month = "8",
day = "15",
doi = "10.1021/es025981p",
language = "English",
volume = "37",
pages = "3531--3536",
journal = "Environmental Science and Technology",
issn = "0013-936X",
publisher = "American Chemical Society",
number = "16",

}

TY - JOUR

T1 - Effect of chelators and reductants on the mobilization of metals from ambient particulate matter

AU - Song, Hee Sang

AU - Bang, Won Gi

AU - Chung, Namhyun

AU - Cho, Yong Sung

AU - Kim, Yoon Shin

AU - Cho, Myung Haing

PY - 2003/8/15

Y1 - 2003/8/15

N2 - Ambient urban particulate matter (PM) contains various transition metals. When the PM is inhaled into the lung, not all but some part of metals from the particles might be mobilized to participate in a reaction that can damage various biomolecules, such as DNA and proteins. The dust particle size as well as organic acids may influence the metal mobilization. Thus, the mobilization of the metal from two standard reference materials (SRM; NIST, USA) and urban PM (PM2.5 and PM10) collected in the Seoul area was measured in the presence of artificial or biological chelator with or without reductant. The degree of the mobilization was higher with the artificial or biological chelator than the control with saline. In some cases, a reductant increased the mobilization as much as about 5 times the control without the reductant. Especially, the mobilization of Fe was greatly influenced by the presence of reductants. In general, the degree of the mobilization of the transition metal was higher with PM2.5 than with PM10. Therefore, it is expected that, considering the previously known toxicities of the transition metals, PM2.5 is more damaging to various biomolecules than PM10. The results also suggest that not the total amount but the mobilizable fraction of the metal in the ambient PM should be considered with regard to the toxicity of the urban particulate matter.

AB - Ambient urban particulate matter (PM) contains various transition metals. When the PM is inhaled into the lung, not all but some part of metals from the particles might be mobilized to participate in a reaction that can damage various biomolecules, such as DNA and proteins. The dust particle size as well as organic acids may influence the metal mobilization. Thus, the mobilization of the metal from two standard reference materials (SRM; NIST, USA) and urban PM (PM2.5 and PM10) collected in the Seoul area was measured in the presence of artificial or biological chelator with or without reductant. The degree of the mobilization was higher with the artificial or biological chelator than the control with saline. In some cases, a reductant increased the mobilization as much as about 5 times the control without the reductant. Especially, the mobilization of Fe was greatly influenced by the presence of reductants. In general, the degree of the mobilization of the transition metal was higher with PM2.5 than with PM10. Therefore, it is expected that, considering the previously known toxicities of the transition metals, PM2.5 is more damaging to various biomolecules than PM10. The results also suggest that not the total amount but the mobilizable fraction of the metal in the ambient PM should be considered with regard to the toxicity of the urban particulate matter.

UR - http://www.scopus.com/inward/record.url?scp=0042663832&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0042663832&partnerID=8YFLogxK

U2 - 10.1021/es025981p

DO - 10.1021/es025981p

M3 - Article

C2 - 12953862

AN - SCOPUS:0042663832

VL - 37

SP - 3531

EP - 3536

JO - Environmental Science and Technology

JF - Environmental Science and Technology

SN - 0013-936X

IS - 16

ER -