Abstract
The effect of fresh gas flow (FGF) on isoflurane concentrations at given vaporizer settings during low-flow anaesthesia was investigated. Ninety patients (American Society of Anaesthesiologists physical status I or II) were randomly allocated to three groups (FGF 1 l/min, FGF 2 l/min and FGF 4 l/min). Anaesthesia was maintained for 10 min with vaporizer setting isoflurane 2 vol% and FGF 4 l/min for full-tissue anaesthetic uptake in a semi-closed circle system. Low-flow anaesthesia was maintained for 20 min with end-tidal isoflurane 1.5 vol% and FGF 2 l/min. FGF was then changed to FGF 1 l/min, FGF 2 l/min or FGF 4 l/min. Measurements during the 20-min period showed that inspired and end-tidal isoflurane concentrations decreased in the FGF 1-l/min group but increased in the FGF 4-l/min group compared with baseline values. No haemodynamic changes were observed. Monitoring of anaesthetic concentrations and appropriate control of vaporizer settings are necessary during low-flow anaesthesia.
| Original language | English |
|---|---|
| Pages (from-to) | 513-519 |
| Number of pages | 7 |
| Journal | Journal of International Medical Research |
| Volume | 33 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - 2005 Jan 1 |
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Keywords
- Breathing systems
- End-tidal concentration
- Fresh gas flow
- Haemodynamic changes
- Isoflurane
- Low-flow anaesthesia
- Vaporizer setting
ASJC Scopus subject areas
- Biochemistry
- Cell Biology
- Biochemistry, medical
Cite this
Effect of fresh gas flow on isoflurane concentrations during low-flow anaesthesia. / Park, J. Y.; Kim, Jae Hwan; Kim, Woon Young; Chang, M. S.; Kim, J. Y.; Shin, Hye Won.
In: Journal of International Medical Research, Vol. 33, No. 5, 01.01.2005, p. 513-519.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Effect of fresh gas flow on isoflurane concentrations during low-flow anaesthesia
AU - Park, J. Y.
AU - Kim, Jae Hwan
AU - Kim, Woon Young
AU - Chang, M. S.
AU - Kim, J. Y.
AU - Shin, Hye Won
PY - 2005/1/1
Y1 - 2005/1/1
N2 - The effect of fresh gas flow (FGF) on isoflurane concentrations at given vaporizer settings during low-flow anaesthesia was investigated. Ninety patients (American Society of Anaesthesiologists physical status I or II) were randomly allocated to three groups (FGF 1 l/min, FGF 2 l/min and FGF 4 l/min). Anaesthesia was maintained for 10 min with vaporizer setting isoflurane 2 vol% and FGF 4 l/min for full-tissue anaesthetic uptake in a semi-closed circle system. Low-flow anaesthesia was maintained for 20 min with end-tidal isoflurane 1.5 vol% and FGF 2 l/min. FGF was then changed to FGF 1 l/min, FGF 2 l/min or FGF 4 l/min. Measurements during the 20-min period showed that inspired and end-tidal isoflurane concentrations decreased in the FGF 1-l/min group but increased in the FGF 4-l/min group compared with baseline values. No haemodynamic changes were observed. Monitoring of anaesthetic concentrations and appropriate control of vaporizer settings are necessary during low-flow anaesthesia.
AB - The effect of fresh gas flow (FGF) on isoflurane concentrations at given vaporizer settings during low-flow anaesthesia was investigated. Ninety patients (American Society of Anaesthesiologists physical status I or II) were randomly allocated to three groups (FGF 1 l/min, FGF 2 l/min and FGF 4 l/min). Anaesthesia was maintained for 10 min with vaporizer setting isoflurane 2 vol% and FGF 4 l/min for full-tissue anaesthetic uptake in a semi-closed circle system. Low-flow anaesthesia was maintained for 20 min with end-tidal isoflurane 1.5 vol% and FGF 2 l/min. FGF was then changed to FGF 1 l/min, FGF 2 l/min or FGF 4 l/min. Measurements during the 20-min period showed that inspired and end-tidal isoflurane concentrations decreased in the FGF 1-l/min group but increased in the FGF 4-l/min group compared with baseline values. No haemodynamic changes were observed. Monitoring of anaesthetic concentrations and appropriate control of vaporizer settings are necessary during low-flow anaesthesia.
KW - Breathing systems
KW - End-tidal concentration
KW - Fresh gas flow
KW - Haemodynamic changes
KW - Isoflurane
KW - Low-flow anaesthesia
KW - Vaporizer setting
UR - http://www.scopus.com/inward/record.url?scp=25844458896&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=25844458896&partnerID=8YFLogxK
U2 - 10.1177/147323000503300506
DO - 10.1177/147323000503300506
M3 - Article
C2 - 16222884
AN - SCOPUS:25844458896
VL - 33
SP - 513
EP - 519
JO - Journal of International Medical Research
JF - Journal of International Medical Research
SN - 0300-0605
IS - 5
ER -