Effect of microencapsulation on viability and other characteristics in Lactobacillus acidophilus ATCC 43121

Se Jin Kim, Seung Yong Cho, Sae Hun Kim, Ok Ja Song, II Shik Shin, Dong Su Cha, Hyun Jin Park

Research output: Contribution to journalArticle

128 Citations (Scopus)

Abstract

Lactobacillus acidophilus ATCC 43121 were microencapsulated with sodium alginate by dropping method. The effects of microencapsulation on the changes in survival rate of the L. acidophilus ATCC 43121 during exposure to artificial gastrointestinal and on the change in heat susceptibility of L. acidophilus ATCC 43121 during the heat treatment were studied. In addition, cholesterol assimilation and intestinal adhesion of non-encapsulated and encapsulated L. acidophilus ATCC 43121 were also investigated to explore the effect of microencapsulation on health beneficial effect of lactic acid bacteria. Non-encapsulated cells were completely destroyed when exposed to artificial gastric juice (AGJ) of pH 1.2 and 1.5, while the treatment declined the viable count of encapsulated samples only by 3 log. Encapsulated cells exhibited a significantly higher resistance to artificial intestinal juice (AIJ) and heat treatment than non-encapsulated samples. The assimilative reductions of cholesterol by non-encapsulated and encapsulated L. acidophilus ATCC 43121 were 35.98% and 32.84%, respectively. However, encapsulation did not significantly (P>0.05) affect the adherence of L. acidophilus ATCC 43121 onto the human intestinal epithelial cell lines HT-29. The microencapsulation effectively protected the microorganisms from heat and acid treatment in delivering the viable cells to intestine without any significant adverse effect on their functionalities.

Original languageEnglish
Pages (from-to)493-500
Number of pages8
JournalLWT - Food Science and Technology
Volume41
Issue number3
DOIs
Publication statusPublished - 2008 Apr 1

Fingerprint

Lactobacillus acidophilus
Microencapsulation
microencapsulation
Drug Compounding
Cholesterol
viability
Hot Temperature
Heat treatment
Sodium alginate
heat treatment
Lactic acid
Encapsulation
Microorganisms
Bacteria
Adhesion
cholesterol
Health
gastric juice
Gastric Juice
sodium alginate

Keywords

  • Alginate
  • Cholesterol assimilation
  • Gastrointestinal tract
  • Heat treatment
  • Intestinal adhesion
  • Lactobacillus acidophilus
  • Microencapsulation

ASJC Scopus subject areas

  • Food Science
  • Engineering (miscellaneous)

Cite this

Effect of microencapsulation on viability and other characteristics in Lactobacillus acidophilus ATCC 43121. / Kim, Se Jin; Cho, Seung Yong; Kim, Sae Hun; Song, Ok Ja; Shin, II Shik; Cha, Dong Su; Park, Hyun Jin.

In: LWT - Food Science and Technology, Vol. 41, No. 3, 01.04.2008, p. 493-500.

Research output: Contribution to journalArticle

Kim, Se Jin ; Cho, Seung Yong ; Kim, Sae Hun ; Song, Ok Ja ; Shin, II Shik ; Cha, Dong Su ; Park, Hyun Jin. / Effect of microencapsulation on viability and other characteristics in Lactobacillus acidophilus ATCC 43121. In: LWT - Food Science and Technology. 2008 ; Vol. 41, No. 3. pp. 493-500.
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